MYBL2
Information MYBL2
- Description
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
- Full Name
MYB proto-oncogene like 2
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 7
- Biotypes
- 5
- Peaks
- 154,421
- Non-redundant peaks
- 130,062
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Tryptophan cluster factors
- Familly
- Myb/SANT domain factors
- Sub Familly
- Myb-like factors
Source TFClass
External IDs
- NCBI Gene
- 4605
- Official Gene Name
- MYBL2
- JASPAR
- MA0777
- Ensembl
- ENSG00000101057
- UniProt
- P10244
- Genevisible
- P10244
- RefSeq
- NM_001278610
- Aliases
- B-MYB; BMYB
Datasets Table for MYBL2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MYBL2 | MCF-10A | ctrl | GEO | Homo sapiens | GSE115787 | 3,344 | ||
| MYBL2 | MCF-10A | DOX | GEO | Homo sapiens | GSE115787 | 3,487 | ||
| MYBL2 | HMEC-1 | GEO | Homo sapiens | GSE62425 | 351 | |||
| MYBL2 | Hep-G2 | ENCODE | Homo sapiens | ENCSR581KCO | 67,515 | |||
| MYBL2 | K-562 | ENCODE | Homo sapiens | ENCSR162IEM | 3,477 | |||
| MYBL2 | Hep-G2 | ENCODE | Homo sapiens | ENCSR000BRO | 13,912 | |||
| MYBL2 | A-673 | GEO | Homo sapiens | GSE119971 | 62,335 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |