MYBL2

Information MYBL2

Description

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]

Full Name

MYB proto-oncogene like 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
7
Biotypes
5
Peaks
154,421
Non-redundant peaks
130,062

TF Classification

Super Class
Helix-turn-helix domains
Class
Tryptophan cluster factors
Familly
Myb/SANT domain factors
Sub Familly
Myb-like factors

Source TFClass

External IDs

NCBI Gene
4605
Official Gene Name
MYBL2
JASPAR
MA0777
Ensembl
ENSG00000101057
UniProt
P10244
Genevisible
P10244
RefSeq
NM_001278610
Aliases
B-MYB; BMYB
All peaks MYBL2
Download BED file
Non redundant peaks MYBL2
Download BED file
SEQUENCES MYBL2
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for MYBL2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MYBL2 MCF-10A ctrl GEO Homo sapiens GSE115787 3,344
MYBL2 MCF-10A DOX GEO Homo sapiens GSE115787 3,487
MYBL2 HMEC-1 GEO Homo sapiens GSE62425 351
MYBL2 Hep-G2 ENCODE Homo sapiens ENCSR581KCO 67,515
MYBL2 K-562 ENCODE Homo sapiens ENCSR162IEM 3,477
MYBL2 Hep-G2 ENCODE Homo sapiens ENCSR000BRO 13,912
MYBL2 A-673 GEO Homo sapiens GSE119971 62,335
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks