Mad

The gene Mothers against dpp is referred to in FlyBase by the symbol DmelMad (CG12399, FBgn0011648). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:3146056..3159643. Its molecular function is described by 10 unique terms, many of which group under: protein binding; DNA-binding transcription factor activity; molecular function regulator; DNA-binding transcription factor activity, RNA polymerase II-specific; transcription regulator activity. It is involved in the biological process described with 28 unique terms, many of which group under: maintenance of cell number; multi-organism reproductive process; stem cell population maintenance; photoreceptor cell fate specification; regulation of cell cycle. 100 alleles are reported. The phenotypes of these alleles manifest in: synapse; multivesicular body; sensory system neuron; axon terminus; cortical zone of lymph gland primary lobe. The phenotypic classes of alleles include: phenotype; cell number defective; increased cell number; lethal - all die before end of second instar larval stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis.

Mothers against dpp

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6