Met

The gene Methoprene-tolerant is referred to in FlyBase by the symbol DmelMet (CG1705, FBgn0002723). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:11616124..11621280. Its molecular function is described by 6 unique terms, many of which group under: binding; protein binding; DNA-binding transcription factor activity; transcription regulator activity; molecular function regulator. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; regulation of developmental process; regulation of transcription by RNA polymerase II; negative regulation of programmed cell death. 40 alleles are reported. The phenotypes of these alleles manifest in: sensory organ cell; male terminalia; anatomical cluster; embryonic/larval fat body; adult abdominal segment. The phenotypic classes of alleles include: female semi-fertile; increased mortality; flight defective; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.

Methoprene-tolerant

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6