Mlf

The gene Myelodysplasia/myeloid leukemia factor is referred to in FlyBase by the symbol DmelMlf (CG8295, FBgn0034051). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (7 unique). Gene sequence location is 2R:15935893..15940073. Its molecular function is described by: transcription factor binding; chaperone binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; regulation of cell proliferation involved in compound eye morphogenesis; protein stabilization; positive regulation of crystal cell differentiation. 22 alleles are reported. The phenotypes of these alleles manifest in: segmental subdivision of integument; primary lobe of embryonic/larval lymph gland; immaterial anatomical entity; late embryo; pigment cell. The phenotypic classes of alleles include: visible; phenotype; increased mortality during development; lethal - all die before end of second instar larval stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages.

Myelodysplasia/myeloid leukemia factor

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6