NAB2

Information NAB2

Description

This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Full Name

NGFI-A binding protein 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
2,293
Non-redundant peaks
2,293

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
4665
Official Gene Name
NAB2
JASPAR
Ensembl
ENSG00000166886
UniProt
Q15742
Genevisible
Q15742
RefSeq
NM_001330305
Aliases
MADER
All peaks NAB2
Download BED file
Non redundant peaks NAB2
Download BED file
SEQUENCES NAB2
Download FASTA file
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Datasets Table for NAB2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
NAB2 HL-60 PMA GEO Homo sapiens GSE106359 2,293
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks