NCOA3
Information NCOA3
- Description
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, probably via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit (By similarity). {ECO:0000250, ECO:0000269|PubMed:10823921}.
- Full Name
nuclear receptor coactivator 3
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 34,746
- Non-redundant peaks
- 34,746
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 17979
- Official Gene Name
- Ncoa3
- JASPAR
- MGI
- MGI:1276535
- Ensembl
- ENSMUSG00000027678
- UniProt
- O09000
- Genevisible
- O09000
- RefSeq
- NM_008679
- Aliases
- 2010305B15Rik; AIB1; AW321064; Actr; Aib1; KAT13B; RAC3; Rac3; Src3; TRAM-1; TRAM1; Tram-1; Tram1; bHLHe42; p/Cip; pCIP; pCip