NCOR1

Information NCOR1

Description

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]

Full Name

nuclear receptor corepressor 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
9
Biotypes
4
Peaks
158,142
Non-redundant peaks
124,334

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
9611
Official Gene Name
NCOR1
JASPAR
Ensembl
ENSG00000141027
UniProt
O75376
Genevisible
O75376
RefSeq
NM_001190438
Aliases
KIAA1047; MGC104216; N-CoR; N-CoR1; PPP1R109; TRAC1; hCIT529I10; hN-CoR
All peaks NCOR1
Download BED file
Non redundant peaks NCOR1
Download BED file
SEQUENCES NCOR1
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for NCOR1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
NCOR1 HEK293T SIGSP2 GEO Homo sapiens GSE35197 1,753
NCOR1 HEK293T SICTR GEO Homo sapiens GSE35197 13,123
NCOR1 OCI-Ly1 GEO Homo sapiens GSE29282 8,511
NCOR1 K-562 ENCODE Homo sapiens ENCSR298JCG 5,785
NCOR1 K-562 ENCODE Homo sapiens ENCSR910JAI 17,706
NCOR1 K-562 ENCODE Homo sapiens ENCSR798ILC 33,416
NCOR1 K-562 ENCODE Homo sapiens ENCSR000ATY 817
NCOR1 LS180 GEO Homo sapiens GSE39277 37,930
NCOR1 LS180 125 GEO Homo sapiens GSE39277 39,101
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks