NELFA
Information NELFA
- Description
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008]
- Full Name
negative elongation factor complex member A
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 15
- Biotypes
- 3
- Peaks
- 133,472
- Non-redundant peaks
- 30,082
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
Datasets Table for NELFA
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
---|---|---|---|---|---|---|---|---|
NELFA | BT-474 | INHHDAC | ENA | Homo sapiens | ERP010664 | 12,051 | ||
NELFA | BT-474 | ENA | Homo sapiens | ERP010664 | 5,558 | |||
NELFA | HeLa | Flavo-PJ34-10min-H2O2 | GEO | Homo sapiens | GSE100742 | 6,922 | ||
NELFA | HeLa | 40min-Flavo-0-H2O2 | GEO | Homo sapiens | GSE93931 | 5,149 | ||
NELFA | HeLa | Flavo-0-H2O2 | GEO | Homo sapiens | GSE100742 | 9,473 | ||
NELFA | HeLa | Flavo-35min-H2O2 | GEO | Homo sapiens | GSE100742 | 11,987 | ||
NELFA | HeLa | 40min-Flavo-PJ34-10min-H2O2 | GEO | Homo sapiens | GSE93931 | 6,922 | ||
NELFA | HeLa | 1h-Flavo-0-H2O2 | GEO | Homo sapiens | GSE93931 | 9,349 | ||
NELFA | HeLa | 40min-Flavo-10min-H2O2 | GEO | Homo sapiens | GSE93931 | 4,213 | ||
NELFA | HeLa | 40min-Flavo-PJ34-0-H2O2 | GEO | Homo sapiens | GSE93931 | 5,994 | ||
NELFA | HeLa | Flavo-10min-H2O2 | GEO | Homo sapiens | GSE100742 | 4,213 | ||
NELFA | HeLa | Flavo-PJ34-0-H2O2 | GEO | Homo sapiens | GSE100742 | 5,994 | ||
NELFA | HeLa | 1h_Flavo-35min-H2O2 | GEO | Homo sapiens | GSE93931 | 11,763 | ||
NELFA | K-562 | NHS | GEO | Homo sapiens | GSE112379 | 15,477 | ||
NELFA | K-562 | HS | GEO | Homo sapiens | GSE112379 | 18,407 | ||
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |