NELFE
Information NELFE
- Description
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity). The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (By similarity). Provides the strongest RNA binding activity of the NELF complex and may initially recruit the NELF complex to RNA (By similarity). {ECO:0000250|UniProtKB:P18615}.(Source UnitProtKB).
- Full Name
negative elongation factor complex member E, Rdbp
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 5
- Biotypes
- 3
- Peaks
- 53,569
- Non-redundant peaks
- 23,430
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 27632
- Official Gene Name
- Nelfe
- JASPAR
- MGI
- MGI:102744
- Ensembl
- ENSMUSG00000024369
- UniProt
- P19426
- Genevisible
- P19426
- RefSeq
- NM_138580
- Aliases
- D17H6S45; NELF-E; RD; Rdbp
Datasets Table for NELFE
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| NELFE | CH12-LX | ENCODE | Mus musculus | ENCSR000ERD | 11,866 | |||
| NELFE | MEL | ENCODE | Mus musculus | ENCSR000ETU | 15,002 | |||
| NELFE | BMDM | LPS-DEX-1h | GEO | Mus musculus | GSE109131 | 8,655 | ||
| NELFE | BMDM | LPS-3h | GEO | Mus musculus | GSE109131 | 3,995 | ||
| NELFE | BMDM | LPS-0h | GEO | Mus musculus | GSE109131 | 14,051 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |