NELFE

Information NELFE

Description

The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. [provided by RefSeq, Jul 2008]

Full Name

negative elongation factor complex member E

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
10
Biotypes
5
Peaks
322,244
Non-redundant peaks
178,558

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
7936
Official Gene Name
NELFE
JASPAR
Ensembl
ENSG00000233801
UniProt
P18615
Genevisible
P18615
RefSeq
NM_002904
Aliases
D6S45; NELF-E; RD; RDBP; RDP
All peaks NELFE
Download BED file
Non redundant peaks NELFE
Download BED file
SEQUENCES NELFE
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for NELFE

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
NELFE HeLa GEO Homo sapiens GSE125534 60,325
NELFE HeLa DOX GEO Homo sapiens GSE125534 66,119
NELFE K-562 NHS GEO Homo sapiens GSE112379 70,233
NELFE K-562 HS GEO Homo sapiens GSE112379 53,254
NELFE DLD-1 NELFCD-AID GEO Homo sapiens GSE144786 18,839
NELFE DLD-1 NELFE-AID GEO Homo sapiens GSE144786 8,095
NELFE DLD-1 NELFCD-AID_treated GEO Homo sapiens GSE144786 10,213
NELFE U2OS GEO Homo sapiens GSE90555 8,246
NELFE HCT-116 GEO Homo sapiens GSE132705 12,442
NELFE HCT-116 KAP1-KO GEO Homo sapiens GSE132705 14,478
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks