NFATC1
Information NFATC1
- Description
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription (PubMed:9388475). Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (By similarity). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (PubMed:23990468, PubMed:26644563). {ECO:0000250|UniProtKB:O95644, ECO:0000269|PubMed:23990468, ECO:0000269|PubMed:9388475, ECO:0000303|PubMed:26644563}.
- Full Name
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 12,900
- Non-redundant peaks
- 9,767
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 18018
- Official Gene Name
- Nfatc1
- JASPAR
- MGI
- MGI:102469
- Ensembl
- ENSMUSG00000033016
- UniProt
- O88942
- Genevisible
- O88942
- RefSeq
- NM_198429
- Aliases
- 2210017P03Rik; AI449492; AV076380; NF-ATc; NFAT2; NFATc; Nfatcb
Datasets Table for NFATC1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| NFATC1 | back-skin | GEO | Mus musculus | GSE52328 | 1,852 | |||
| NFATC1 | NKC | shSTAT3 | GEO | Mus musculus | GSE39969 | 3,963 | ||
| NFATC1 | NKC | GEO | Mus musculus | GSE39969 | 7,085 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |