NFE2
Information NFE2
- Description
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron. {ECO:0000269|PubMed:9558374}.
- Full Name
nuclear factor, erythroid derived 2
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 5
- Biotypes
- 2
- Peaks
- 14,348
- Non-redundant peaks
- 11,417
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
Datasets Table for NFE2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| NFE2 | liver | MK2D | GEO | Mus musculus | GSE42110 | 449 | ||
| NFE2 | liver | RBC2D | GEO | Mus musculus | GSE42110 | 1,308 | ||
| NFE2 | liver | MK5D | GEO | Mus musculus | GSE42110 | 4,174 | ||
| NFE2 | spleen | GEO | Mus musculus | GSE47492 | 7,620 | |||
| NFE2 | liver | GEO | Mus musculus | GSE42249 | 797 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |