NFYB

Information NFYB

Description

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008]

Full Name

nuclear transcription factor Y subunit beta

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
5
Biotypes
4
Peaks
86,026
Non-redundant peaks
54,578

TF Classification

Super Class
Other all-alpha-helical DNA-binding domains
Class
Heteromeric CCAAT-binding factors
Familly
Heteromeric CCAAT-binding factors
Sub Familly
None

Source TFClass

External IDs

NCBI Gene
4801
Official Gene Name
NFYB
JASPAR
MA0502
Ensembl
ENSG00000120837
UniProt
P25208
Genevisible
P25208
RefSeq
NM_006166
Aliases
CBF-A; CBF-B; HAP3; NF-YB
All peaks NFYB
Download BED file
Non redundant peaks NFYB
Download BED file
SEQUENCES NFYB
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for NFYB

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
NFYB Hep-G2 ENCODE Homo sapiens ENCSR935GZV 40,416
NFYB K-562 GEO Homo sapiens GSE26439 15,252
NFYB K-562 ENCODE Homo sapiens ENCSR000EGQ 13,231
NFYB GM12878 ENCODE Homo sapiens ENCSR000DNM 8,892
NFYB HeLa-S3 ENCODE Homo sapiens ENCSR000DNR 8,235
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks