NKX2-2

Information NKX2-2

Description

Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (PubMed:11076772). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (PubMed:19759004). {ECO:0000269|PubMed:11076772, ECO:0000269|PubMed:19759004}.(Source UnitProtKB).

Full Name

NK2 homeobox 2

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
4
Biotypes
4
Peaks
91,073
Non-redundant peaks
75,410

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
18088
Official Gene Name
Nkx2-2
JASPAR
MGI
MGI:97347
Ensembl
ENSMUSG00000027434
UniProt
P42586
Genevisible
P42586
RefSeq
NM_010919
Aliases
Nkx-2.2; Nkx2.2; tinman
All peaks NKX2-2
Download BED file
Non redundant peaks NKX2-2
Download BED file
SEQUENCES NKX2-2
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for NKX2-2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
NKX2-2 NPC GEO Mus musculus GSE61673 16,625
NKX2-2 MIN6 GEO Mus musculus GSE79785 11,995
NKX2-2 OPC GEO Mus musculus GSE73921 19,876
NKX2-2 oligodendrocyte GEO Mus musculus GSE73921 42,577
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks