NKX6-1
Information NKX6-1
- Description
Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Required for the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition (PubMed:11076772). Involved in transcriptional regulation of the insulin gene. Together with NKX2-2 and IRX3, restricts the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals. {ECO:0000269|PubMed:10830170, ECO:0000269|PubMed:11076772}.(Source UnitProtKB).
- Full Name
NK6 homeobox 1
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 17,429
- Non-redundant peaks
- 17,429
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 18096
- Official Gene Name
- Nkx6-1
- JASPAR
- MGI
- MGI:1206039
- Ensembl
- ENSMUSG00000035187
- UniProt
- Q99MA9
- Genevisible
- Q99MA9
- RefSeq
- NM_144955
- Aliases
- NKX6A; Nkx6.1