NR4A1
Information NR4A1
- Description
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation (By similarity). Plays a role in the vascular response to injury (PubMed:22427340). {ECO:0000250, ECO:0000269|PubMed:22427340}.(Source UnitProtKB).
- Full Name
nuclear receptor subfamily 4, group A, member 1
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 82,522
- Non-redundant peaks
- 82,299
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 15370
- Official Gene Name
- Nr4a1
- JASPAR
- MGI
- MGI:1352454
- Ensembl
- ENSMUSG00000023034
- UniProt
- P12813
- Genevisible
- P12813
- RefSeq
- NM_010444
- Aliases
- GFRP1; Gfrp; Hbr-1; Hbr1; Hmr; N10; NGFI-B; NGFIB; NP10; NUR77-1; NUR77-2; Nur77; TIS1; TR3; nur77
Datasets Table for NR4A1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| NR4A1 | Treg | GEO | Mus musculus | GSE70417 | 9,245 | |||
| NR4A1 | macrophage | GEO | Mus musculus | GSE102393 | 73,277 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |