Nf-YB

The gene Nuclear factor Y-box B is referred to in FlyBase by the symbol DmelNf-YB (CG10447, FBgn0032816). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:19736044..19737088. Its molecular function is described by: sequence-specific DNA binding; transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein heterodimerization activity. It is involved in the biological process described with 6 unique terms, many of which group under: regulation of cellular macromolecule biosynthetic process; compound eye photoreceptor cell differentiation; regulation of compound eye photoreceptor cell differentiation; cell death; positive regulation of biosynthetic process. 14 alleles are reported. The phenotypes of these alleles manifest in: photoreceptor cell R7; eye disc posterior to the morphogenetic furrow; eye; ommatidium; interommatidial bristle. The phenotypic classes of alleles include: viable; flight defective; increased cell death; increased occurrence of cell division; mitotic cell cycle defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages.

Nuclear factor Y-box B

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6