OLIG2

Information OLIG2

Description

Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain (PubMed:11955448, PubMed:12121626, PubMed:16908628). Functions together with ZNF488 to promote oligodendrocyte differentiation (PubMed:16908628). Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube (PubMed:11955448, PubMed:12121626). Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development (PubMed:11955448, PubMed:12121626). {ECO:0000269|PubMed:11955448, ECO:0000269|PubMed:12121626, ECO:0000269|PubMed:16908628}.(Source UnitProtKB).

Full Name

oligodendrocyte transcription factor 2

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
17
Biotypes
7
Peaks
249,448
Non-redundant peaks
128,001

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
50913
Official Gene Name
Olig2
JASPAR
MGI
MGI:1355331
Ensembl
ENSMUSG00000039830
UniProt
Q9EQW6
Genevisible
Q9EQW6
RefSeq
NM_016967
Aliases
Bhlhb1; Olg-2; RK17; bHLHe19
All peaks OLIG2
Download BED file
Non redundant peaks OLIG2
Download BED file
SEQUENCES OLIG2
Download FASTA file
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Datasets Table for OLIG2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
OLIG2 medulloblastoma GEO Mus musculus GSE120968 23,227
OLIG2 NPC d4_V5-tag GEO Mus musculus GSE30882 9,879
OLIG2 NPC GEO Mus musculus GSE61673 34,456
OLIG2 brain-tumor GEO Mus musculus GSE80088 49,076
OLIG2 cortex GEO Mus musculus GSE74646 45,867
OLIG2 NSC GEO Mus musculus GSE70872 30,528
OLIG2 NPC d4 GEO Mus musculus GSE30882 42,734
OLIG2 spinal-cord GEO Mus musculus GSE103324 13,681
OLIG2 brain-prefrontal-cortex 2016029 GEO Mus musculus GSE129039 1,172
OLIG2 brain-prefrontal-cortex 2017025 GEO Mus musculus GSE129039 9,119
OLIG2 brain-prefrontal-cortex 2016018 GEO Mus musculus GSE129039 14,175
OLIG2 brain-prefrontal-cortex 201704 GEO Mus musculus GSE129039 3,644
OLIG2 brain-prefrontal-cortex 2017011 GEO Mus musculus GSE129039 22,200
OLIG2 brain-prefrontal-cortex 2017014 GEO Mus musculus GSE129039 28,777
OLIG2 brain-prefrontal-cortex 2017039 GEO Mus musculus GSE129039 19,305
OLIG2 brain-prefrontal-cortex 2018001 GEO Mus musculus GSE129039 4,778
OLIG2 brain-prefrontal-cortex 2018006 GEO Mus musculus GSE129039 21,321
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks