OVOL2
Information OVOL2
- Description
Zinc-finger transcription repressor factor (PubMed:15225875, PubMed:23319585). Plays a critical role in maintaining the identity of epithelial lineages by suppressing epithelial-to mesenchymal transition (EMT) mainly through the repression of ZEB1, an EMT inducer (PubMed:24735878, PubMed:24735879). Positively regulates neuronal differentiation (PubMed:16423343, PubMed:23319585). Suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing MYC and NOTCH1 (By similarity). Important for the correct development of primordial germ cells in embryos (PubMed:28059165). {ECO:0000250|UniProtKB:Q9BRP0, ECO:0000269|PubMed:15225875, ECO:0000269|PubMed:16423343, ECO:0000269|PubMed:23319585, ECO:0000269|PubMed:24735878, ECO:0000269|PubMed:24735879, ECO:0000269|PubMed:28059165}.(Source UnitProtKB).
- Full Name
ovo like zinc finger 2
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 1,384
- Non-redundant peaks
- 1,384
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 107586
- Official Gene Name
- Ovol2
- JASPAR
- MGI
- MGI:1338039
- Ensembl
- ENSMUSG00000037279
- UniProt
- Q8CIV7
- Genevisible
- Q8CIV7
- RefSeq
- NM_152947
- Aliases
- 1810007D21Rik; M-OVO; M-OVO-A; M-OVO-B; Ovol2; Zfp339; movo2
Datasets Table for OVOL2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| OVOL2 | mammary-epithelium | GEO | Mus musculus | GSE53925 | 1,384 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |