PCGF2
Information PCGF2
- Description
The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq, Jul 2008]
- Full Name
polycomb group ring finger 2
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 4
- Biotypes
- 3
- Peaks
- 15,212
- Non-redundant peaks
- 12,644
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 7703
- Official Gene Name
- PCGF2
- JASPAR
- Ensembl
- ENSG00000278644
- UniProt
- P35227
- Genevisible
- P35227
- RefSeq
- NM_001369614
- Aliases
- MEL-18; RNF110; TPFS; ZNF144
Datasets Table for PCGF2
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
---|---|---|---|---|---|---|---|---|
PCGF2 | HEK293T | PCGF2fl | GEO | Homo sapiens | GSE119618 | 1,695 | ||
PCGF2 | NT2-D1 | GEO | Homo sapiens | GSE101538 | 3,197 | |||
PCGF2 | fibroblast | MET | GEO | Homo sapiens | GSE55605 | 6,646 | ||
PCGF2 | fibroblast | OHT | GEO | Homo sapiens | GSE55605 | 3,674 | ||
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |