PGR

Information PGR

Description

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]

Full Name

progesterone receptor

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
35
Biotypes
11
Peaks
902,713
Non-redundant peaks
298,783

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
5241
Official Gene Name
PGR
JASPAR
Ensembl
ENSG00000082175
UniProt
P06401
Genevisible
P06401
RefSeq
NM_000926
Aliases
NR3C3; PR
All peaks PGR
Download BED file
Non redundant peaks PGR
Download BED file
SEQUENCES PGR
Download FASTA file
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Datasets Table for PGR

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
PGR T-47D GEO Homo sapiens GSE31129 28,741
PGR T-47D E2PG GEO Homo sapiens GSE68356 12,513
PGR T-47D E2 GEO Homo sapiens GSE68356 105
PGR T-47D PG GEO Homo sapiens GSE68356 12,292
PGR T-47D R5020 GEO Homo sapiens GSE68355 64,654
PGR T-47D PROG GEO Homo sapiens GSE68355 73,196
PGR T-47D CR3flp_veh GEO Homo sapiens GSE99479 5,899
PGR T-47D GEO Homo sapiens GSE126859 2,585
PGR T-47D VC GEO Homo sapiens GSE113607 9,421
PGR T-47D progesterone_siCEBPA GEO Homo sapiens GSE132649 8,774
PGR T-47D R5020-MTVL GEO Homo sapiens GSE126859 71,136
PGR T-47D progesterone_siCtrl GEO Homo sapiens GSE132649 13,154
PGR T-47D R5020-A1 GEO Homo sapiens GSE126859 55,964
PGR T-47D progesterone GEO Homo sapiens GSE132649 26,474
PGR leiomyoma RU486 GEO Homo sapiens GSE40724 26,649
PGR HUVEC-C PR_PROGESTERON GEO Homo sapiens GSE43786 4,665
PGR MCF-7 PROG GEO Homo sapiens GSE68355 73,279
PGR MCF-7 R5020 GEO Homo sapiens GSE68355 52,169
PGR breast tumor-xenograft_1_E2_P4 GEO Homo sapiens GSE93108 151
PGR breast tumor_Male_30 GEO Homo sapiens GSE104399 22,454
PGR breast tumor_Male_28 GEO Homo sapiens GSE104399 25,642
PGR breast tumor_Male_26 GEO Homo sapiens GSE104399 54,211
PGR hESC GEO Homo sapiens GSE69539 8,690
PGR B hESC GEO Homo sapiens GSE62475 10,530
PGR A hESC GEO Homo sapiens GSE62475 3,996
PGR AB32 GEO Homo sapiens GSE31129 49,437
PGR endometrium Midsecretory GEO Homo sapiens GSE132712 4,991
PGR myometrium TP1 GEO Homo sapiens GSE137550 29,026
PGR myometrium TP2 GEO Homo sapiens GSE137550 22,018
PGR myometrium NP2 GEO Homo sapiens GSE137550 45,119
PGR myometrium NP1 GEO Homo sapiens GSE137550 57,121
PGR T-47D-A R5020 GEO Homo sapiens GSE80358 6,592
PGR T-47D-A E2_R5020 GEO Homo sapiens GSE80358 14,542
PGR T-47D-B R5020 GEO Homo sapiens GSE80358 3,360
PGR T-47D-B E2_R5020 GEO Homo sapiens GSE80358 3,163
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks