PITX1
Information PITX1
- Description
Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. Can independently activate and synergize with PIT-1 on pituitary-specific target gene promoters, thus may subserve functions in generating both precursor and specific cell phenotypes in the anterior pituitary gland and in several other organs. Can activate pituitary transcription of the proopiomelanocortin gene. {ECO:0000250|UniProtKB:P56673, ECO:0000269|PubMed:8675014, ECO:0000269|PubMed:8755540}.(Source UnitProtKB).
- Full Name
paired-like homeodomain transcription factor 1
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 5
- Biotypes
- 2
- Peaks
- 96,994
- Non-redundant peaks
- 72,926
TF Classification
- Familly
- Homeo domain factors
- Sub Familly
- Paired-related HD factors
Source JASPAR
External IDs
- NCBI Gene
- 18740
- Official Gene Name
- Pitx1
- JASPAR
- MA0682.1
- MGI
- MGI:107374
- Ensembl
- ENSMUSG00000021506
- UniProt
- P70314
- Genevisible
- P70314
- RefSeq
- NM_011097
- Aliases
- Bft; P-OTX; Potx; Ptx1
Datasets Table for PITX1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| PITX1 | SCC | 1Mcells_invivo | GEO | Mus musculus | GSE104142 | 356 | ||
| PITX1 | SCC | 20Mcells | GEO | Mus musculus | GSE104142 | 8,325 | ||
| PITX1 | hindlimb | GEO | Mus musculus | GSE100728 | 51,917 | |||
| PITX1 | hindlimb | GEO | Mus musculus | GSE41591 | 35,646 | |||
| PITX1 | SCC | 1Mcells_culture | GEO | Mus musculus | GSE104142 | 750 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |