PPARGC1A
Information PPARGC1A
- Description
This gene encodes a transcriptional coactivator that induces and coordinates gene expression regulating mitochondrial biogenesis, respiration, hepatic gluconeogenesis, thermogenic program in brown fat and muscle fiber-type switching. Mice lacking the encoded protein exhibit reduced thermogenic capacity, hyperactivity and resistance to diet-induced obesity. Mice lacking the encoded protein specifically in the heart exhibit peripartum cardiomyopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- Full Name
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 13,690
- Non-redundant peaks
- 13,622
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 19017
- Official Gene Name
- Ppargc1a
- JASPAR
- MGI
- MGI:1342774
- Ensembl
- ENSMUSG00000029167
- UniProt
- O70343
- Genevisible
- O70343
- RefSeq
- NM_008904
- Aliases
- A830037N07Rik; Gm11133; PGC-1; PPAR Gamma Coactivator-1; PPARGC-1-alpha; Pgc-1alpha; Pgc-1alphaa; Pgc1; Pgco1; Ppargc1
Datasets Table for PPARGC1A
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| PPARGC1A | liver | GEO | Mus musculus | GSE57852 | 125 | |||
| PPARGC1A | C2C12 | GEO | Mus musculus | GSE51178 | 13,432 | |||
| PPARGC1A | K779me | liver | K779me | GEO | Mus musculus | GSE57852 | 133 | |
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |