PPARGC1A

Information PPARGC1A

Description

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]

Full Name

PPARG coactivator 1 alpha

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
170
Non-redundant peaks
170

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
10891
Official Gene Name
PPARGC1A
JASPAR
Ensembl
ENSG00000109819
UniProt
Q9UBK2
Genevisible
Q9UBK2
RefSeq
NM_001330751
Aliases
LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1
All peaks PPARGC1A
Download BED file
Non redundant peaks PPARGC1A
Download BED file
SEQUENCES PPARGC1A
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for PPARGC1A

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
PPARGC1A Hep-G2 ENCODE Homo sapiens ENCSR000EEQ 170
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks