PRDM5

Information PRDM5

Description

Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes (By similarity). May regulate the expression of proteins involved in extracellular matrix development and maintenance, connective tissue components and molecules regulating cell migration and adhesion. May cause G2/M arrest and apoptosis in cancer cells (By similarity). {ECO:0000250}.(Source UnitProtKB).

Full Name

PR domain containing 5

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
2
Biotypes
1
Peaks
7,876
Non-redundant peaks
7,416

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
70779
Official Gene Name
Prdm5
JASPAR
MGI
MGI:1918029
Ensembl
ENSMUSG00000029913
UniProt
Q9CXE0
Genevisible
Q9CXE0
RefSeq
Aliases
4432417F03Rik; 6530401I24Rik; E130112L17Rik; PFM2
All peaks PRDM5
Download BED file
Non redundant peaks PRDM5
Download BED file
SEQUENCES PRDM5
Download FASTA file
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Datasets Table for PRDM5

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
PRDM5 MEF lacz-lacz GEO Mus musculus GSE51816 857
PRDM5 MEF GEO Mus musculus GSE51816 7,019
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks