RAD21

Information RAD21

Description

[Double-strand-break repair protein rad21 homolog]: As a member of the cohesin complex, involved in sister chromatid cohesion from the time of DNA replication in S phase to their segregation in mitosis, a function that is essential for proper chromosome segregation, post-replicative DNA repair, and the prevention of inappropriate recombination between repetitive regions. The cohesin complex may also play a role in spindle pole assembly during mitosis (By similarity). In interphase, cohesins may function in the control of gene expression by binding to numerous sites within the genome (PubMed:18237772). May control RUNX1 gene expression. Binds to and represses APOB gene promoter (By similarity). May play a role in embryonic gut development, possibly through the regulation of enteric neuron development (By similarity). {ECO:0000250|UniProtKB:O60216, ECO:0000250|UniProtKB:Q6TEL1, ECO:0000269|PubMed:18237772}.; [64-kDa C-terminal product]: May promote apoptosis. {ECO:0000250|UniProtKB:O60216}.(Source UnitProtKB).

Full Name

RAD21 cohesin complex component

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
130
Biotypes
36
Peaks
4,683,490
Non-redundant peaks
507,932

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
19357
Official Gene Name
Rad21
JASPAR
MGI
MGI:108016
Ensembl
ENSMUSG00000022314
UniProt
Q61550
Genevisible
Q61550
RefSeq
NM_009009
Aliases
SCC1; mHR21; mKIAA0078

External links
All peaks RAD21
Download BED file
Non redundant peaks RAD21
Download BED file
SEQUENCES RAD21
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for RAD21

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
RAD21 spleen 96h GEO Mus musculus GSE61443 12,918
RAD21 spleen stimulated GEO Mus musculus GSE130264 59,996
RAD21 fibroblast Xist-del GEO Mus musculus GSE67516 26,473
RAD21 fibroblast GEO Mus musculus GSE67516 38,070
RAD21 CH12-LX ENCODE Mus musculus ENCSR000ERK 50,527
RAD21 embryonic-midbrain MB-E105 GEO Mus musculus GSE84793 9,229
RAD21 MEL dimethyl-sulfoxide_2-percent_5-day ENCODE Mus musculus ENCSR000ETT 36,094
RAD21 NPC ES-derived_Smchd1-neg GEO Mus musculus GSE99991 19,375
RAD21 G1E-ER4 asyn GEO Mus musculus GSE129997 13,734
RAD21 G1E-ER4 mid-G1 GEO Mus musculus GSE129997 15,503
RAD21 G1E-ER4 prometa GEO Mus musculus GSE129997 254
RAD21 G1E-ER4 early-G1 GEO Mus musculus GSE129997 9,125
RAD21 G1E-ER4 ana-telo GEO Mus musculus GSE129997 7,595
RAD21 G1E-ER4 late-G1 GEO Mus musculus GSE129997 19,317
RAD21 liver NIPBL GEO Mus musculus GSE93431 1,338
RAD21 liver GEO Mus musculus GSE102997 68,892
RAD21 liver TAM GEO Mus musculus GSE93431 23,725
RAD21 G4 INV-DEL GEO Mus musculus GSE116790 21,394
RAD21 G4 INV GEO Mus musculus GSE116790 35,796
RAD21 HPC-7 Ery_Luc GEO Mus musculus GSE129478 78,999
RAD21 HPC-7 serum-starved GEO Mus musculus GSE100835 23,439
RAD21 HPC-7 shStag2 GEO Mus musculus GSE129478 60,978
RAD21 HPC-7 Myelo_Luc GEO Mus musculus GSE129478 52,357
RAD21 HPC-7 Ery_shStag2 GEO Mus musculus GSE129478 72,276
RAD21 MEF Wapl-ff_cre GEO Mus musculus GSE129526 69,252
RAD21 MEF Wapl-ff GEO Mus musculus GSE129526 77,295
RAD21 MEF GEO Mus musculus GSE99195 76,190
RAD21 AML12 shU GEO Mus musculus GSE95113 32,885
RAD21 AML12 GEO Mus musculus GSE95113 51,673
RAD21 lymphoma N4-mut GEO Mus musculus GSE137216 58,784
RAD21 lymphoma DMSO GEO Mus musculus GSE137216 38,030
RAD21 lymphoma chimera1 GEO Mus musculus GSE137216 46,338
RAD21 lymphoma mut_Fl-Ctcf GEO Mus musculus GSE137216 69,890
RAD21 lymphoma GEO Mus musculus GSE130264 45,316
RAD21 lymphoma mut_BORIS GEO Mus musculus GSE137216 42,209
RAD21 lymphoma N3-mut GEO Mus musculus GSE137216 58,667
RAD21 lymphoma chimeraAZF GEO Mus musculus GSE137216 23,646
RAD21 lymphoma N5-mut GEO Mus musculus GSE137216 52,615
RAD21 lymphoma BORIS GEO Mus musculus GSE137216 53,013
RAD21 lymphoma mut GEO Mus musculus GSE137216 74,041
RAD21 lymphoma N2-mut GEO Mus musculus GSE137216 69,613
RAD21 lymphoma stimulated GEO Mus musculus GSE130264 40,029
RAD21 lymphoma mut_Nterm_11ZFs GEO Mus musculus GSE137216 35,252
RAD21 astrocyte GEO Mus musculus GSE48938 12,829
RAD21 thymocyte GEO Mus musculus GSE48763 13,616
RAD21 thymocyte DP GEO Mus musculus GSE109909 36,146
RAD21 thymocyte DN GEO Mus musculus GSE109909 10,696
RAD21 pre-B-cell GEO Mus musculus GSE109909 27,735
RAD21 pre-pro-B-cell GEO Mus musculus GSE40173 3,053
RAD21 CH12 APR-60h_wt GEO Mus musculus GSE121355 61,833
RAD21 CH12 wt GEO Mus musculus GSE121355 71,578
RAD21 cerebellum Ai32-fl-fl_Atoh1-CRE_opt GEO Mus musculus GSE127995 21,571
RAD21 myeloid-progenitor GEO Mus musculus GSE93127 54,833
RAD21 primary-B-cell activated GEO Mus musculus GSE99195 73,914
RAD21 B-cell resting GEO Mus musculus GSE82144 55,064
RAD21 erythroid WT GEO Mus musculus GSE97869 47,907
RAD21 brain CB GEO Mus musculus GSE35140 25,055
RAD21 brain BC GEO Mus musculus GSE35140 26,649
RAD21 embryonic-limb-bud FL-E105 GEO Mus musculus GSE84793 7,337
RAD21 embryonic-limb-bud HL-E135 GEO Mus musculus GSE84793 1,320
RAD21 embryonic-limb-bud HL-E115 GEO Mus musculus GSE84793 7,034
RAD21 embryonic-limb-bud FL-E115 GEO Mus musculus GSE84793 6,413
RAD21 mESC D0_DKO GEO Mus musculus GSE74055 20,082
RAD21 mESC D3_DKO GEO Mus musculus GSE74055 16,107
RAD21 mESC dCD GEO Mus musculus GSE74055 61,490
RAD21 mESC D1-5 GEO Mus musculus GSE74055 23,166
RAD21 mESC D3 GEO Mus musculus GSE74055 24,844
RAD21 mESC D0 GEO Mus musculus GSE74055 1,410
RAD21 mESC D2 GEO Mus musculus GSE74055 21,650
RAD21 mESC D1-5_DKO GEO Mus musculus GSE74055 34,160
RAD21 mESC INV GEO Mus musculus GSE116790 32,592
RAD21 mESC D1_DKO GEO Mus musculus GSE74055 29,520
RAD21 mESC ADNP-KO GEO Mus musculus GSE125129 51,438
RAD21 mESC GEO Mus musculus GSE90994 38,921
RAD21 mESC D2-5_DKO GEO Mus musculus GSE74055 12,667
RAD21 mESC C59 GEO Mus musculus GSE90994 19,017
RAD21 mESC D1 GEO Mus musculus GSE74055 16,876
RAD21 mESC GEO Mus musculus GSE24029 12,700
RAD21 pro-B-cell Block GEO Mus musculus GSE130213 60,356
RAD21 pro-B-cell Ig2bdel GEO Mus musculus GSE130213 77,287
RAD21 pro-B-cell GEO Mus musculus GSE40173 12,821
RAD21 EBs GEO Mus musculus GSE24029 6,842
RAD21 limb GEO Mus musculus GSE101714 52,440
RAD21 limb i4i5ZRS GEO Mus musculus GSE123386 24,404
RAD21 limb del8-13rXII GEO Mus musculus GSE101714 15,735
RAD21 limb GEO Mus musculus GSE123386 23,084
RAD21 distal-forelimb GEO Mus musculus GSE101714 16,197
RAD21 NSC GEO Mus musculus GSE48938 16,012
RAD21 bone-marrow GEO Mus musculus GSE26257 13,353
RAD21 bone-marrow GEO Mus musculus GSE83960 50,338
RAD21 BMDM IL4-6h GEO Mus musculus GSE107456 39,349
RAD21 BMDM IL4-24h GEO Mus musculus GSE107456 42,579
RAD21 BMDM LPS-6h GEO Mus musculus GSE108583 59,488
RAD21 BMDM GEO Mus musculus GSE107456 34,441
RAD21 BMDM IL4-1h GEO Mus musculus GSE107456 34,336
RAD21 mOSN GEO Mus musculus GSE112153 27,942
RAD21 cerebellum Ai32-fl-fl GEO Mus musculus GSE127995 24,199
RAD21 neutrophil GEO Mus musculus GSE93127 43,496
RAD21 lymphoma AZF-mut GEO Mus musculus GSE137216 19,970
RAD21 lymphoma stim_i3DBEs GEO Mus musculus GSE130264 22,764
RAD21 lymphoma 11ZFs-Cterm GEO Mus musculus GSE137216 29,555
RAD21 lymphoma ABA GEO Mus musculus GSE137216 79,311
RAD21 lymphoma GEO Mus musculus GSE137216 74,001
RAD21 lymphoma Ctcf-mut GEO Mus musculus GSE137216 24,888
RAD21 small-intestinal-crypt GEO Mus musculus GSE59283 1,860
RAD21 bone-marrow KO GEO Mus musculus GSE83960 26,027
RAD21 spleen 0h GEO Mus musculus GSE61443 6,839
RAD21 spleen 48h GEO Mus musculus GSE61443 4,842
RAD21 spleen GEO Mus musculus GSE130264 75,549
RAD21 BMDM LPS-1h GEO Mus musculus GSE108583 70,367
RAD21 MEL ENCODE Mus musculus ENCSR000ETS 38,258
RAD21 limb i4i5 GEO Mus musculus GSE123386 41,204
RAD21 MEF GEO Mus musculus GSE129526 65,109
RAD21 MEF Smc3-ff GEO Mus musculus GSE129526 42,414
RAD21 NPC ES-derived GEO Mus musculus GSE99991 15,947
RAD21 pro-B-cell GEO Mus musculus GSE27214 39,836
RAD21 pro-B-cell GEO Mus musculus GSE47766 13,829
RAD21 pro-B-cell GEO Mus musculus GSE130213 57,881
RAD21 embryonic-limb-bud HL-E105 GEO Mus musculus GSE84793 9,148
RAD21 embryonic-limb-bud FL-E135 GEO Mus musculus GSE84793 126
RAD21 mESC D2_DKO GEO Mus musculus GSE74055 21,425
RAD21 mESC dCas9 GEO Mus musculus GSE74055 55,551
RAD21 mESC GEO Mus musculus GSE81676 43,074
RAD21 mESC D2-5 GEO Mus musculus GSE74055 18,153
RAD21 mESC GEO Mus musculus GSE125129 51,460
RAD21 mESC GEO Mus musculus GSE74055 46,119
RAD21 HPC-7 TPO-30min GEO Mus musculus GSE100835 35,299
RAD21 HPC-7 shSmc1a GEO Mus musculus GSE129478 79,873
RAD21 HPC-7 Luc GEO Mus musculus GSE129478 70,620
RAD21 CH12 APR-60h GEO Mus musculus GSE121355 74,127
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks