RARA

Information RARA

Description

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]

Full Name

retinoic acid receptor alpha

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
7
Biotypes
4
Peaks
59,249
Non-redundant peaks
48,198

TF Classification

Super Class
Zinc-coordinating DNA-binding domains
Class
Nuclear receptors with C4 zinc fingers
Familly
Thyroid hormone receptor-related factors (NR1)
Sub Familly
Retinoic acid receptors (NR1B)

Source TFClass

External IDs

NCBI Gene
5914
Official Gene Name
RARA
JASPAR
MA1149
Ensembl
ENSG00000131759
UniProt
P10276
Genevisible
P10276
RefSeq
NM_000964
Aliases
NR1B1; RAR
All peaks RARA
Download BED file
Non redundant peaks RARA
Download BED file
SEQUENCES RARA
Download FASTA file
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Datasets Table for RARA

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
RARA TSU-1621MT GEO Homo sapiens GSE60477 25,455
RARA U-937 ATRA-treated_RAR GEO Homo sapiens GSE98006 2,875
RARA SK-N-SH GEO Homo sapiens GSE69119 1,841
RARA hiPSC D3 GEO Homo sapiens GSE109172 7,485
RARA hiPSC D4 GEO Homo sapiens GSE109172 12,170
RARA hiPSC D2 GEO Homo sapiens GSE132532 2,805
RARA hiPSC D5 GEO Homo sapiens GSE132532 6,618
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks