RARB
Information RARB
- Description
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (By similarity). The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element (By similarity). In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (PubMed:19389355). {ECO:0000250|UniProtKB:P10826, ECO:0000269|PubMed:19389355}.(Source UnitProtKB).
- Full Name
retinoic acid receptor, beta
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 34,670
- Non-redundant peaks
- 30,321
TF Classification
- Familly
- Nuclear receptors with C4 zinc fingers
- Sub Familly
- Thyroid hormone receptor-related factors (NR1)
Source JASPAR
Datasets Table for RARB
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| RARB | liver | RA | GEO | Mus musculus | GSE53736 | 21,098 | ||
| RARB | liver | GEO | Mus musculus | GSE53736 | 6,112 | |||
| RARB | brain | GEO | Mus musculus | GSE67829 | 7,460 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |