RBBP4
Information RBBP4
- Description
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. {ECO:0000250|UniProtKB:Q09028}.(Source UnitProtKB).
- Full Name
retinoblastoma binding protein 4, chromatin remodeling factor
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 3
- Biotypes
- 1
- Peaks
- 34,863
- Non-redundant peaks
- 32,682
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 19646
- Official Gene Name
- Rbbp4
- JASPAR
- MGI
- MGI:1194912
- Ensembl
- ENSMUSG00000057236
- UniProt
- Q60972
- Genevisible
- Q60972
- RefSeq
- NM_009030
- Aliases
- CAF-1 p48 subunit; RBAP48; mRbAp48
Datasets Table for RBBP4
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| RBBP4 | NIH3T3 | WT | GEO | Mus musculus | GSE110382 | 2,065 | ||
| RBBP4 | NIH3T3 | GEO | Mus musculus | GSE110382 | 31,021 | |||
| RBBP4 | NIH3T3 | KD | GEO | Mus musculus | GSE110382 | 1,777 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |