RELA

Information RELA

Description

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Full Name

RELA proto-oncogene, NF-kB subunit

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
124
Biotypes
36
Peaks
3,085,337
Non-redundant peaks
546,239

TF Classification

Super Class
Immunoglobulin fold
Class
Rel homology region (RHR) factors
Familly
NF-kappaB-related factors
Sub Familly
NF-kappaB p65 subunit-like factors

Source TFClass

External IDs

NCBI Gene
5970
Official Gene Name
RELA
JASPAR
MA0107
Ensembl
ENSG00000173039
UniProt
Q04206
Genevisible
Q04206
RefSeq
NM_001145138
Aliases
CMCU; NFKB3; p65

External links
All peaks RELA
Download BED file
Non redundant peaks RELA
Download BED file
SEQUENCES RELA
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for RELA

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
RELA MCF-7 TNFa_45m GEO Homo sapiens GSE67295 14,562
RELA MCF-7 TNF GEO Homo sapiens GSE59530 1,572
RELA MCF-7 Veh GEO Homo sapiens GSE67295 27,873
RELA MCF-7 E2_TNF GEO Homo sapiens GSE59530 2,681
RELA MCF-7 E2 GEO Homo sapiens GSE59530 941
RELA MCF-7 IL1b_45m GEO Homo sapiens GSE67295 27,097
RELA SGBS GEO Homo sapiens GSE64233 23,154
RELA SGBS TNF GEO Homo sapiens GSE64233 75,024
RELA L1236 GEO Homo sapiens GSE63736 612
RELA HEK293 30_min GEO Homo sapiens GSE89017 2,131
RELA HEK293 60_min GEO Homo sapiens GSE89017 690
RELA HEK293 TNF-15min GEO Homo sapiens GSE75562 569
RELA HEK293 GEO Homo sapiens GSE89017 1,169
RELA HEK293 TNF-30min GEO Homo sapiens GSE75562 2,720
RELA HEK293 TNF-1h GEO Homo sapiens GSE75562 27,261
RELA HEK293 15min GEO Homo sapiens GSE89017 259
RELA HEK293 TNF GEO Homo sapiens GSE121361 115
RELA FaDu LPS GEO Homo sapiens GSE132018 75,187
RELA FaDu GEO Homo sapiens GSE132018 1,612
RELA IMR-90 TNF GEO Homo sapiens GSE43070 22,640
RELA IMR-90 GEO Homo sapiens GSE43070 803
RELA THP-1 eGFP-Pam3csk-4h GEO Homo sapiens GSE103477 19,400
RELA KB IL GEO Homo sapiens GSE52469 25,746
RELA KB GEO Homo sapiens GSE52469 18,957
RELA KB 5Z GEO Homo sapiens GSE64223 4,394
RELA KB 5Z_IL GEO Homo sapiens GSE64223 3,943
RELA HeLa E39I-0H GEO Homo sapiens GSE116284 456
RELA HeLa WT-1H GEO Homo sapiens GSE116284 3,094
RELA HeLa ctrl-1H GEO Homo sapiens GSE116284 1,285
RELA LNCaP SICTR_TNFA GEO Homo sapiens GSE83860 29,235
RELA LNCaP DHT_TNFA GEO Homo sapiens GSE83860 20,450
RELA LNCaP TNFA GEO Homo sapiens GSE83860 2,572
RELA LNCaP SIFOXA1_TNFA GEO Homo sapiens GSE83860 37,589
RELA THP-1 eGFP-Pam3csk-0h GEO Homo sapiens GSE103477 1,624
RELA K-562 ENCODE Homo sapiens ENCSR772EEN 11,357
RELA HUVEC-C GEO Homo sapiens GSE53998 295
RELA HUVEC-C TNF_0M GEO Homo sapiens GSE34500 900
RELA HUVEC-C TNF GEO Homo sapiens GSE53998 16,724
RELA HUVEC-C TNF_30M GEO Homo sapiens GSE34500 29,814
RELA HUVEC-C Scr GEO Homo sapiens GSE87552 7,123
RELA HUVEC-C TNF GEO Homo sapiens GSE43070 7,568
RELA HUVEC-C TNF_JQ1 GEO Homo sapiens GSE53998 19,534
RELA HUVEC-C TNF-60min GEO Homo sapiens GSE121890 24,541
RELA HUVEC-C GEO Homo sapiens GSE121890 3,950
RELA HUVEC-C TNF-30min GEO Homo sapiens GSE121890 30,801
RELA BJAB GEO Homo sapiens GSE117250 15,432
RELA BJAB 4h-activation GEO Homo sapiens GSE117250 11,374
RELA BJAB 1h-activation GEO Homo sapiens GSE117250 22,075
RELA MCF-7 GEO Homo sapiens GSE59530 790
RELA MCF-7 E2_45m GEO Homo sapiens GSE67295 2,932
RELA GM19193 ENCODE Homo sapiens ENCSR000EBM 4,814
RELA GM19099 ENCODE Homo sapiens ENCSR000EBI 24,642
RELA GM18951 ENCODE Homo sapiens ENCSR000EBD 6,538
RELA GM18526 ENCODE Homo sapiens ENCSR000EBA 7,344
RELA GM18505 ENCODE Homo sapiens ENCSR000EAW 7,025
RELA GM15510 ENCODE Homo sapiens ENCSR000EAQ 8,989
RELA GM12892 ENCODE Homo sapiens ENCSR000EAN 3,924
RELA GM12891 ENCODE Homo sapiens ENCSR000EAI 22,511
RELA GM12878 ENCODE Homo sapiens ENCSR664POU 24,825
RELA GM12878 ENCODE Homo sapiens ENCSR000EAG 24,519
RELA GM10847 ENCODE Homo sapiens ENCSR000DYM 6,633
RELA 786-O GEO Homo sapiens GSE109953 24,984
RELA 786-O GEO Homo sapiens GSE86092 68,337
RELA AC16 TNFA GEO Homo sapiens GSE51169 6,815
RELA AC16 GEO Homo sapiens GSE51169 1,226
RELA Huh-7 IL1 GEO Homo sapiens GSE89212 2,078
RELA 786-M1A GEO Homo sapiens GSE98012 14,153
RELA U2OS 10Gy_2h_recovery GEO Homo sapiens GSE109996 1,166
RELA U2OS GEO Homo sapiens GSE109996 2,245
RELA HDF DMSO GEO Homo sapiens GSE77225 4,525
RELA HDF NUTLIN GEO Homo sapiens GSE77225 10,585
RELA CD4 Th1_BAY GEO Homo sapiens GSE62482 18,324
RELA CD4 Th1_DMSO GEO Homo sapiens GSE62482 21,695
RELA SW480 0h_TNFa GEO Homo sapiens GSE102796 3,393
RELA SW480 16h_TNFa GEO Homo sapiens GSE102796 37,372
RELA HeLa-B2 P65KD_DMSO GEO Homo sapiens GSE24518 7,393
RELA HeLa-B2 GRKD_TA_TNFA GEO Homo sapiens GSE24518 10,511
RELA HeLa-B2 TA GEO Homo sapiens GSE24518 1,357
RELA HeLa-B2 DMSO GEO Homo sapiens GSE24518 3,157
RELA HeLa-B2 GRKD_DMSO GEO Homo sapiens GSE24518 12,452
RELA HeLa-B2 P65KD_TA_TNFA GEO Homo sapiens GSE24518 8,413
RELA HeLa-B2 TNFA GEO Homo sapiens GSE24518 21,828
RELA HeLa-B2 TA_TNFA GEO Homo sapiens GSE24518 18,283
RELA aortic-endothelial-cell IL1B_D53 GEO Homo sapiens GSE139377 60,610
RELA aortic-endothelial-cell IL1B_D10 GEO Homo sapiens GSE139377 37,381
RELA aortic-endothelial-cell IL1B_D11 GEO Homo sapiens GSE139377 34,907
RELA aortic-endothelial-cell IL1B_D14 GEO Homo sapiens GSE139377 64,279
RELA aortic-endothelial-cell IL1B_D16 GEO Homo sapiens GSE139377 67,697
RELA aortic-endothelial-cell IL1B_D38 GEO Homo sapiens GSE139377 59,543
RELA aortic-endothelial-cell IL1B_D39 GEO Homo sapiens GSE139377 68,301
RELA aortic-endothelial-cell IL1B_D33 GEO Homo sapiens GSE139377 60,986
RELA aortic-endothelial-cell IL1B_D31 GEO Homo sapiens GSE139377 31,807
RELA aortic-endothelial-cell IL1B_D35 GEO Homo sapiens GSE139377 36,153
RELA aortic-endothelial-cell IL1B_D8 GEO Homo sapiens GSE139377 48,896
RELA aortic-endothelial-cell IL1B_D2 GEO Homo sapiens GSE139377 67,506
RELA aortic-endothelial-cell IL1B_D3 GEO Homo sapiens GSE139377 35,901
RELA aortic-endothelial-cell IL1B_D6 GEO Homo sapiens GSE139377 54,191
RELA aortic-endothelial-cell IL1B_D7 GEO Homo sapiens GSE139377 79,904
RELA aortic-endothelial-cell IL1B_D4 GEO Homo sapiens GSE139377 67,872
RELA aortic-endothelial-cell IL1B_D9 GEO Homo sapiens GSE139377 75,363
RELA aortic-endothelial-cell IL1B_D49 GEO Homo sapiens GSE139377 47,918
RELA aortic-endothelial-cell IL1B_D47 GEO Homo sapiens GSE139377 67,889
RELA aortic-endothelial-cell IL1B_D45 GEO Homo sapiens GSE139377 49,521
RELA aortic-endothelial-cell IL1B_D41 GEO Homo sapiens GSE139377 46,008
RELA aortic-endothelial-cell IL1B_D40 GEO Homo sapiens GSE139377 63,569
RELA aortic-endothelial-cell IL1B_D28 GEO Homo sapiens GSE139377 34,012
RELA aortic-endothelial-cell IL1B_D25 GEO Homo sapiens GSE139377 50,326
RELA aortic-endothelial-cell IL1B_D27 GEO Homo sapiens GSE139377 51,160
RELA aortic-endothelial-cell IL1B_D26 GEO Homo sapiens GSE139377 61,563
RELA aortic-endothelial-cell IL1B_D21 GEO Homo sapiens GSE139377 74,700
RELA aortic-endothelial-cell IL1B_D22 GEO Homo sapiens GSE139377 46,388
RELA aortic-endothelial-cell IL1B_D13 GEO Homo sapiens GSE139377 61,667
RELA aortic-endothelial-cell IL1B_D24 GEO Homo sapiens GSE139377 18,107
RELA mammary-epithelial-cell EGF GEO Homo sapiens GSE71069 3,684
RELA mammary-epithelial-cell GEO Homo sapiens GSE71069 2,225
RELA mammary-epithelial-cell IL1 GEO Homo sapiens GSE71069 9,162
RELA HAEC TNFa_4h GEO Homo sapiens GSE89970 77,019
RELA HAEC IL1b_4h GEO Homo sapiens GSE89970 57,966
RELA HAEC GEO Homo sapiens GSE89970 31,743
RELA Detroit-562 LPS GEO Homo sapiens GSE91018 29,232
RELA Detroit-562 tri-DAP GEO Homo sapiens GSE91018 23,328
RELA Detroit-562 Poly-I GEO Homo sapiens GSE91018 39,894
RELA Detroit-562 Pam2CSK4 GEO Homo sapiens GSE91018 24,008
RELA Detroit-562 TNFa GEO Homo sapiens GSE91018 38,268
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks