RFX2
Information RFX2
- Description
Transcription factor that acts as a key regulator of spermatogenesis (PubMed:26248850, PubMed:26162102, PubMed:26853561). Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function (PubMed:26162102, PubMed:26853561). Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters (PubMed:15229132, PubMed:26162102). Probably activates transcription of the testis-specific histone gene H1-6 (PubMed:15229132). {ECO:0000269|PubMed:15229132, ECO:0000269|PubMed:26162102, ECO:0000269|PubMed:26248850, ECO:0000269|PubMed:26853561}.(Source UnitProtKB).
- Full Name
regulatory factor X, 2 (influences HLA class II expression)
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 12,707
- Non-redundant peaks
- 12,707
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 19725
- Official Gene Name
- Rfx2
- JASPAR
- MGI
- MGI:106583
- Ensembl
- ENSMUSG00000024206
- UniProt
- P48379
- Genevisible
- P48379
- RefSeq
- NM_027787
- Aliases
- 5430432H19Rik