RFXAP

Information RFXAP

Description

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. [provided by RefSeq, Jul 2008]

Full Name

regulatory factor X associated protein

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
26,228
Non-redundant peaks
26,228

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
5994
Official Gene Name
RFXAP
JASPAR
Ensembl
ENSG00000133111
UniProt
O00287
Genevisible
O00287
RefSeq
NM_000538
Aliases
All peaks RFXAP
Download BED file
Non redundant peaks RFXAP
Download BED file
SEQUENCES RFXAP
Download FASTA file
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Datasets Table for RFXAP

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
RFXAP Hep-G2 ENCODE Homo sapiens ENCSR524RLU 26,228
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks