RUNX1

Information RUNX1

Description

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Full Name

RUNX family transcription factor 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
55
Biotypes
26
Peaks
1,279,785
Non-redundant peaks
368,526

TF Classification

Super Class
Immunoglobulin fold
Class
Runt domain factors
Familly
Runt-related factors
Sub Familly
None

Source TFClass

External IDs

NCBI Gene
861
Official Gene Name
RUNX1
JASPAR
MA0002
Ensembl
ENSG00000159216
UniProt
Q01196
Genevisible
Q01196
RefSeq
NM_001001890
Aliases
AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2A2; PEBP2aB; PEBP2alpha

External links
All peaks RUNX1
Download BED file
Non redundant peaks RUNX1
Download BED file
SEQUENCES RUNX1
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for RUNX1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
RUNX1 SKNO-1 GEO Homo sapiens GSE23730 54,702
RUNX1 ALL-SIL GEO Homo sapiens GSE102209 12,929
RUNX1 U-937 GEO Homo sapiens GSE65427 9,408
RUNX1 CD34 FETAL GEO Homo sapiens GSE70660 6,290
RUNX1 CD34 GEO Homo sapiens GSE64862 47,132
RUNX1 CD34 ADULT GEO Homo sapiens GSE70660 13,531
RUNX1 mut CD34 GEO Homo sapiens GSE111917 39,938
RUNX1 MV4-11 GEO Homo sapiens GSE79899 53,562
RUNX1 ME-1 Human-leukemia_AI-10-49 GEO Homo sapiens GSE101789 10,218
RUNX1 ME-1 GEO Homo sapiens GSE46044 34,844
RUNX1 ME-1 GEO Homo sapiens GSE117138 29,480
RUNX1 ME-1 Con GEO Homo sapiens GSE128771 26,289
RUNX1 ME-1 CBFB-MYH11-KD GEO Homo sapiens GSE117138 26,289
RUNX1 ME-1 KD GEO Homo sapiens GSE128771 29,480
RUNX1 VCaP DHT24H GEO Homo sapiens GSE58428 58,139
RUNX1 THP-1 GEO Homo sapiens GSE79899 37,525
RUNX1 PBMC GEO Homo sapiens GSE85524 103
RUNX1 697 GEO Homo sapiens GSE138031 50,969
RUNX1 HL-60 GEO Homo sapiens GSE107553 10,001
RUNX1 Jurkat GEO Homo sapiens GSE76181 44,066
RUNX1 Jurkat GEO Homo sapiens GSE42575 5,019
RUNX1 Jurkat GEO Homo sapiens GSE29180 10,040
RUNX1 Jurkat GEO Homo sapiens GSE85524 39,533
RUNX1 Jurkat GEO Homo sapiens GSE68976 34,976
RUNX1 MCF-10A mitotic GEO Homo sapiens GSE121370 554
RUNX1 MCF-10A GEO Homo sapiens GSE129314 14,974
RUNX1 MCF-10A asynchronous GEO Homo sapiens GSE121370 2,631
RUNX1 MCF-10A GEO Homo sapiens GSE121370 981
RUNX1 CCRF-CEM GEO Homo sapiens GSE33850 620
RUNX1 Kasumi-1 GEO Homo sapiens GSE45738 25,157
RUNX1 Kasumi-1 GEO Homo sapiens GSE62847 21,152
RUNX1 Kasumi-1 GEO Homo sapiens GSE65427 17,321
RUNX1 NB4 GEO Homo sapiens GSE81992 63,134
RUNX1 K-562 ENCODE Homo sapiens ENCSR414TYY 3,367
RUNX1 K-562 ENCODE Homo sapiens ENCSR588AKU 13,877
RUNX1 keratinocyte GEO Homo sapiens GSE98483 6,208
RUNX1 MCF-7 GEO Homo sapiens GSE75070 181
RUNX1 NALM-6 GEO Homo sapiens GSE126300 49,523
RUNX1 NALM-6 GEO Homo sapiens GSE109377 3,651
RUNX1 SKH1 GEO Homo sapiens GSE87283 37,553
RUNX1 SKH1 RUNX1-EVI1_KD GEO Homo sapiens GSE87283 53,362
RUNX1 SKH1 10d GEO Homo sapiens GSE87283 48,644
RUNX1 H9 DOX-0_HA GEO Homo sapiens GSE137670 110
RUNX1 H9 DOX-0 GEO Homo sapiens GSE137670 2,177
RUNX1 H9 DOX-5_HA GEO Homo sapiens GSE137670 17,015
RUNX1 hiPSC DOX_d34 GEO Homo sapiens GSE111917 2,615
RUNX1 hiPSC DOX_d31 GEO Homo sapiens GSE111917 675
RUNX1 epididymis HEE_R1881 GEO Homo sapiens GSE109061 2,653
RUNX1 epididymis HEE GEO Homo sapiens GSE109061 56,713
RUNX1 AML Blast GEO Homo sapiens GSE60130 47,123
RUNX1 AML age-50-70 GEO Homo sapiens GSE111821 9,858
RUNX1 AML GEO Homo sapiens GSE111917 11,341
RUNX1 AML bone-marrow GEO Homo sapiens GSE111821 13,613
RUNX1 AML GEO Homo sapiens GSE111821 28,697
RUNX1 BCP-ALL patient1 GEO Homo sapiens GSE109377 39,842
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks