RUNX1T1

Information RUNX1T1

Description

Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Can repress transactivation mediated by TCF12 (By similarity). Acts as a negative regulator of adipogenesis (PubMed:23527555). {ECO:0000250|UniProtKB:Q06455, ECO:0000269|PubMed:23527555}.(Source UnitProtKB).

Full Name

RUNX1 translocation partner 1

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
4
Biotypes
3
Peaks
113,337
Non-redundant peaks
84,111

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
12395
Official Gene Name
Runx1t1
JASPAR
MGI
MGI:104793
Ensembl
ENSMUSG00000006586
UniProt
Q61909
Genevisible
Q61909
RefSeq
NM_009822
Aliases
Cbfa2t1h; ETO; MTG8
All peaks RUNX1T1
Download BED file
Non redundant peaks RUNX1T1
Download BED file
SEQUENCES RUNX1T1
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for RUNX1T1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
RUNX1T1 floating-progenitor-cell uninduced GEO Mus musculus GSE64589 57,811
RUNX1T1 hemogenic-endothelium induced GEO Mus musculus GSE64589 23,973
RUNX1T1 myeloid-progenitor-expansion induced GEO Mus musculus GSE64589 14,000
RUNX1T1 hemogenic-endothelium uninduced GEO Mus musculus GSE64589 17,553
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks