RUNX2

Information RUNX2

Description

This gene encodes a member of the runt domain-containing family of transcription factors. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Sep 2015]

Full Name

runt related transcription factor 2

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
14
Biotypes
4
Peaks
748,552
Non-redundant peaks
223,908

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
12393
Official Gene Name
Runx2
JASPAR
MGI
MGI:99829
Ensembl
ENSMUSG00000039153
UniProt
Q08775
Genevisible
Q08775
RefSeq
NM_009820
Aliases
AML3; Cbf; Cbfa-1; Cbfa1; LS3; Osf2; PEBP2 alpha A; PEBP2aA; Pebp2a1; Pebpa2a; SL3-3 enhancer factor 1; polyomavirus enhancer binding factor 2 (PEBP

External links
All peaks RUNX2
Download BED file
Non redundant peaks RUNX2
Download BED file
SEQUENCES RUNX2
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for RUNX2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
RUNX2 MSC veh_d7 GEO Mus musculus GSE79813 47,448
RUNX2 MSC veh_adipogenic GEO Mus musculus GSE79813 53,584
RUNX2 MSC veh_d15 GEO Mus musculus GSE79813 61,823
RUNX2 MC3T3-E1 OB GEO Mus musculus GSE51513 79,905
RUNX2 MC3T3-E1 diff GEO Mus musculus GSE41920 61,505
RUNX2 MC3T3-E1 d28 GEO Mus musculus GSE54013 57,659
RUNX2 MC3T3-E1 GEO Mus musculus GSE41920 57,756
RUNX2 bone-marrow d21 GEO Mus musculus GSE76074 71,118
RUNX2 MLL-AF9 KO GEO Mus musculus GSE120063 53,682
RUNX2 MLL-AF9 GEO Mus musculus GSE120063 56,310
RUNX2 bone-marrow d7 GEO Mus musculus GSE76074 27,039
RUNX2 bone-marrow d0 GEO Mus musculus GSE76074 26,091
RUNX2 MC3T3-E1 d0 GEO Mus musculus GSE54013 20,903
RUNX2 MC3T3-E1 POB GEO Mus musculus GSE51513 73,729
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks