SIN3B
Information SIN3B
- Description
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression (PubMed:22476904). {ECO:0000269|PubMed:10620510, ECO:0000269|PubMed:22476904, ECO:0000269|PubMed:7889570}.(Source UnitProtKB).
- Full Name
transcriptional regulator, SIN3B (yeast)
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 2
- Biotypes
- 1
- Peaks
- 6,556
- Non-redundant peaks
- 5,336
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 20467
- Official Gene Name
- Sin3b
- JASPAR
- MGI
- MGI:107158
- Ensembl
- ENSMUSG00000031622
- UniProt
- Q62141
- Genevisible
- Q62141
- RefSeq
- Aliases
- 2810430C10Rik
Datasets Table for SIN3B
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SIN3B | C2C12 | myotube | GEO | Mus musculus | GSE22554 | 3,696 | ||
| SIN3B | C2C12 | myoblast | GEO | Mus musculus | GSE22554 | 2,860 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |