SINHCAF
Information SINHCAF
- Description
Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway (By similarity). Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is essential for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming (PubMed:28554894). {ECO:0000250|UniProtKB:Q9NP50, ECO:0000269|PubMed:28554894}.(Source UnitProtKB).
- Full Name
SIN3-HDAC complex associated factor
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 28,898
- Non-redundant peaks
- 28,898
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 56306
- Official Gene Name
- Sinhcaf
- JASPAR
- MGI
- MGI:1929091
- Ensembl
- ENSMUSG00000039985
- UniProt
- Q8C8M1
- Genevisible
- Q8C8M1
- RefSeq
- Aliases
- Fam60a; Pptcs1; Tera