SINHCAF

Information SINHCAF

Description

Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway (By similarity). Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is essential for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming (PubMed:28554894). {ECO:0000250|UniProtKB:Q9NP50, ECO:0000269|PubMed:28554894}.(Source UnitProtKB).

Full Name

SIN3-HDAC complex associated factor

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
28,898
Non-redundant peaks
28,898

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
56306
Official Gene Name
Sinhcaf
JASPAR
MGI
MGI:1929091
Ensembl
ENSMUSG00000039985
UniProt
Q8C8M1
Genevisible
Q8C8M1
RefSeq
Aliases
Fam60a; Pptcs1; Tera
All peaks SINHCAF
Download BED file
Non redundant peaks SINHCAF
Download BED file
SEQUENCES SINHCAF
Download FASTA file
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Datasets Table for SINHCAF

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SINHCAF mESC GEO Mus musculus GSE81081 28,898
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks