SIRT3

Information SIRT3

Description

SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]

Full Name

sirtuin 3

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
55
Non-redundant peaks
55

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
23410
Official Gene Name
SIRT3
JASPAR
Ensembl
ENSG00000142082
UniProt
Q9NTG7
Genevisible
Q9NTG7
RefSeq
NM_001017524
Aliases
SIR2L3
All peaks SIRT3
Download BED file
Non redundant peaks SIRT3
Download BED file
SEQUENCES SIRT3
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for SIRT3

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SIRT3 U2OS GEO Homo sapiens GSE41000 55
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks