SKIL

Information SKIL

Description

The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Full Name

SKI like proto-oncogene

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
2
Biotypes
2
Peaks
67,060
Non-redundant peaks
63,092

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
6498
Official Gene Name
SKIL
JASPAR
Ensembl
ENSG00000136603
UniProt
P12757
Genevisible
P12757
RefSeq
NM_001145097
Aliases
SNO; SnoA; SnoI; SnoN
All peaks SKIL
Download BED file
Non redundant peaks SKIL
Download BED file
SEQUENCES SKIL
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for SKIL

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SKIL K-562 ENCODE Homo sapiens ENCSR336DXE 19,141
SKIL GM12878 ENCODE Homo sapiens ENCSR212YKD 47,919
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks