SMARCA4

Information SMARCA4

Description

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Full Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
84
Biotypes
28
Peaks
2,850,960
Non-redundant peaks
720,183

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
6597
Official Gene Name
SMARCA4
JASPAR
Ensembl
ENSG00000127616
UniProt
P51532
Genevisible
P51532
RefSeq
NM_001128844
Aliases
BAF190; BAF190A; BRG1; CSS4; FLJ39786; MRD16; RTPS2; SNF2; SNF2-BETA; SNF2L4; SNF2LB; SWI2; hSNF2b

External links
All peaks SMARCA4
Download BED file
Non redundant peaks SMARCA4
Download BED file
SEQUENCES SMARCA4
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for SMARCA4

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SMARCA4 MCF-7 ARID1A-KO_4-OHT_clone14 GEO Homo sapiens GSE123284 42,092
SMARCA4 MCF-7 GEO Homo sapiens GSE123284 64,627
SMARCA4 MCF-7 parental GEO Homo sapiens GSE123284 56,787
SMARCA4 MCF-7 shJUN GEO Homo sapiens GSE128445 4,566
SMARCA4 MCF-7 ARID1A-KO GEO Homo sapiens GSE140185 18,369
SMARCA4 MCF-7 GEO Homo sapiens GSE140185 51,557
SMARCA4 MCF-7 GEO Homo sapiens GSE128445 7,400
SMARCA4 A-549 AG15689 GEO Homo sapiens GSE132290 20,064
SMARCA4 A-549 AG15688 GEO Homo sapiens GSE132290 20,645
SMARCA4 A-549 AG15680 GEO Homo sapiens GSE132290 11,016
SMARCA4 A-549 AG15687 GEO Homo sapiens GSE132290 2,815
SMARCA4 A-549 AG15686 GEO Homo sapiens GSE132290 18,642
SMARCA4 A-549 AG15685 GEO Homo sapiens GSE132290 70,808
SMARCA4 A-549 AG15684 GEO Homo sapiens GSE132290 49,045
SMARCA4 A-549 AG15720 GEO Homo sapiens GSE132290 40,421
SMARCA4 A-549 AG15721 GEO Homo sapiens GSE132290 59,921
SMARCA4 A-549 AG15722 GEO Homo sapiens GSE132290 67,427
SMARCA4 A-549 AG15723 GEO Homo sapiens GSE132290 54,528
SMARCA4 A-549 AG15724 GEO Homo sapiens GSE132290 44,832
SMARCA4 A-549 AG15725 GEO Homo sapiens GSE132290 76,943
SMARCA4 A-549 AG15677 GEO Homo sapiens GSE132290 77,333
SMARCA4 A-549 AG15678 GEO Homo sapiens GSE132290 66,814
SMARCA4 A-549 AG15679 GEO Homo sapiens GSE132290 10,674
SMARCA4 A-549 AG15690 GEO Homo sapiens GSE132290 4,931
SMARCA4 BT-16 Dox GEO Homo sapiens GSE71504 18,432
SMARCA4 BT-16 NoDox GEO Homo sapiens GSE71504 1,430
SMARCA4 22Rv1 GEO Homo sapiens GSE115615 30,934
SMARCA4 22Rv1 PTEN-KO GEO Homo sapiens GSE115615 35,106
SMARCA4 WA09 GEO Homo sapiens GSE105028 1,790
SMARCA4 WA09 heat-shock GEO Homo sapiens GSE105028 3,056
SMARCA4 Aska-SS GEO Homo sapiens GSE108025 33,408
SMARCA4 Aska-SS shSSX GEO Homo sapiens GSE108025 44,169
SMARCA4 BIN-67 lentivirus-SMARCA4-T910M GEO Homo sapiens GSE117734 51,941
SMARCA4 BIN-67 lentivirus-SMARCA4-K785R GEO Homo sapiens GSE117734 48,218
SMARCA4 BIN-67 lentivirus-SMARCA4 GEO Homo sapiens GSE117734 70,755
SMARCA4 501-mel SHSOX10 GEO Homo sapiens GSE61965 39,980
SMARCA4 501-mel SHMITF GEO Homo sapiens GSE61965 25,609
SMARCA4 501-mel SHCTR GEO Homo sapiens GSE61965 48,491
SMARCA4 MCF-10A GEO Homo sapiens GSE74716 27,090
SMARCA4 NGP GEO Homo sapiens GSE134626 34,136
SMARCA4 NGP ARID1A-mut2 GEO Homo sapiens GSE134626 52,465
SMARCA4 NGP ARID1A-mut1 GEO Homo sapiens GSE134626 18,835
SMARCA4 NGP ARID1A-het GEO Homo sapiens GSE134626 28,761
SMARCA4 HeLa GEO Homo sapiens GSE137250 1,329
SMARCA4 LNCaP r1881 GEO Homo sapiens GSE94682 11,960
SMARCA4 HS-SY-2 HA-tagged GEO Homo sapiens GSE108926 48,113
SMARCA4 K-562 ENCODE Homo sapiens ENCSR587OQL 71,236
SMARCA4 K-562 ENCODE Homo sapiens ENCSR643VTW 61,311
SMARCA4 CTV-1 FLAG_SPI1-mut GEO Homo sapiens GSE128835 39,296
SMARCA4 TTC-549 NoDox GEO Homo sapiens GSE71504 6,131
SMARCA4 TTC-549 Dox GEO Homo sapiens GSE71504 6,701
SMARCA4 SYO-1 GEO Homo sapiens GSE108025 14,889
SMARCA4 MCF-7 ARID1A-KO_clone14 GEO Homo sapiens GSE123284 38,174
SMARCA4 MCF-7 ARID1A-KO_4-OHT GEO Homo sapiens GSE123284 11,716
SMARCA4 G-401 Dox GEO Homo sapiens GSE71504 913
SMARCA4 G-401 NoDox GEO Homo sapiens GSE71504 508
SMARCA4 TTC-1240 SMARCB1-FL GEO Homo sapiens GSE124903 40,739
SMARCA4 TTC-1240 empty GEO Homo sapiens GSE124903 25,615
SMARCA4 TTC-1240 R377H GEO Homo sapiens GSE124903 55,790
SMARCA4 TTC-1240 delC GEO Homo sapiens GSE124903 49,346
SMARCA4 TTC-1240 GEO Homo sapiens GSE124903 51,261
SMARCA4 TOV-21G GEO Homo sapiens GSE110448 9,306
SMARCA4 TOV-21G resistant GEO Homo sapiens GSE110448 8,310
SMARCA4 NCI-H1703 GEO Homo sapiens GSE121755 12,200
SMARCA4 CTV-1 FLAG GEO Homo sapiens GSE128835 62,053
SMARCA4 CTV-1 DSG GEO Homo sapiens GSE128835 62,582
SMARCA4 CTV-1 delQ GEO Homo sapiens GSE128835 38,135
SMARCA4 CTV-1 delA GEO Homo sapiens GSE128835 35,304
SMARCA4 CTV-1 DSG_SPI1-mut GEO Homo sapiens GSE128835 39,322
SMARCA4 hiPSC GEO Homo sapiens GSE124903 68,594
SMARCA4 hiPSC WT GEO Homo sapiens GSE124903 48,997
SMARCA4 J-Lat GFP-Clone-A72_JQ1 GEO Homo sapiens GSE100266 9,212
SMARCA4 J-Lat GFP-Clone-A72_DMSO GEO Homo sapiens GSE100266 22,387
SMARCA4 HeLa-S3 ENCODE Homo sapiens ENCSR000EZC 5,175
SMARCA4 HCT-116 GEO Homo sapiens GSE71510 1,883
SMARCA4 endometrial-epithelial-cells KO GEO Homo sapiens GSE106660 73,314
SMARCA4 NSC GEO Homo sapiens GSE125033 66,835
SMARCA4 NPC siCT GEO Homo sapiens GSE122631 25,599
SMARCA4 NPC K755R-siAP GEO Homo sapiens GSE122631 64,871
SMARCA4 NPC K755R-siCT GEO Homo sapiens GSE122631 47,947
SMARCA4 NPC R1159Q GEO Homo sapiens GSE122631 11,028
SMARCA4 NPC siSOX GEO Homo sapiens GSE122631 27,938
SMARCA4 NPC K755R-pos GEO Homo sapiens GSE122631 17,570
SMARCA4 NPC GEO Homo sapiens GSE122631 507
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks