SMARCE1

Information SMARCE1

Description

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 2008]

Full Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
4
Biotypes
4
Peaks
107,332
Non-redundant peaks
101,566

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
6605
Official Gene Name
SMARCE1
JASPAR
Ensembl
ENSG00000073584
UniProt
Q969G3
Genevisible
Q969G3
RefSeq
NM_003079
Aliases
BAF57; CSS5
All peaks SMARCE1
Download BED file
Non redundant peaks SMARCE1
Download BED file
SEQUENCES SMARCE1
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for SMARCE1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SMARCE1 MCF-7 ENCODE Homo sapiens ENCSR431TLD 30,070
SMARCE1 K-562 ENCODE Homo sapiens ENCSR157TCS 62,590
SMARCE1 Hep-G2 ENCODE Homo sapiens ENCSR968QDP 608
SMARCE1 HMLE-Twist-ER 125nM_4OHT GEO Homo sapiens GSE96933 14,064
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks