SMC3
Information SMC3
- Description
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement. {ECO:0000269|PubMed:10375619}.(Source UnitProtKB).
- Full Name
structural maintenance of chromosomes 3
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 32
- Biotypes
- 10
- Peaks
- 882,940
- Non-redundant peaks
- 183,559
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 13006
- Official Gene Name
- Smc3
- JASPAR
- MGI
- MGI:1339795
- Ensembl
- ENSMUSG00000024974
- UniProt
- Q9CW03
- Genevisible
- Q9CW03
- RefSeq
- NM_007790
- Aliases
- Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD
Datasets Table for SMC3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SMC3 | CH12-LX | ENCODE | Mus musculus | ENCSR000ERG | 35,306 | |||
| SMC3 | liver | TAM | GEO | Mus musculus | GSE93431 | 16,429 | ||
| SMC3 | liver | NIPBL | GEO | Mus musculus | GSE93431 | 2,202 | ||
| SMC3 | MEF | Wapl-pos | GEO | Mus musculus | GSE41602 | 55,879 | ||
| SMC3 | MEF | Stag1-KO | GEO | Mus musculus | GSE32319 | 31,414 | ||
| SMC3 | MEF | Wapl-neg | GEO | Mus musculus | GSE41602 | 58,035 | ||
| SMC3 | MEF | GEO | Mus musculus | GSE32319 | 13,446 | |||
| SMC3 | Th17 | GEO | Mus musculus | GSE63778 | 31,944 | |||
| SMC3 | embryonic-brain | TSTS | GEO | Mus musculus | GSE117184 | 1,870 | ||
| SMC3 | embryonic-brain | GEO | Mus musculus | GSE117184 | 11,500 | |||
| SMC3 | B-cell | activated_EQbiot | GEO | Mus musculus | GSE98119 | 20,346 | ||
| SMC3 | B-cell | activated_KAbiot | GEO | Mus musculus | GSE98119 | 15,460 | ||
| SMC3 | mESC | GEO | Mus musculus | GSE22562 | 8,079 | |||
| SMC3 | bone-marrow | GEO | Mus musculus | GSE90958 | 36,067 | |||
| SMC3 | bone-marrow | 15min-AcD1 | GEO | Mus musculus | GSE90958 | 49,089 | ||
| SMC3 | bone-marrow | 15min-AcD2 | GEO | Mus musculus | GSE90958 | 30,777 | ||
| SMC3 | bone-marrow | 1h-AcD2 | GEO | Mus musculus | GSE90958 | 2,473 | ||
| SMC3 | bone-marrow | 1h-AcD1 | GEO | Mus musculus | GSE90958 | 8,581 | ||
| SMC3 | bone-marrow | 30min-AcD1 | GEO | Mus musculus | GSE90958 | 41,021 | ||
| SMC3 | bone-marrow | 30min-AcD2 | GEO | Mus musculus | GSE90958 | 45,220 | ||
| SMC3 | bone-marrow | 1h | GEO | Mus musculus | GSE90958 | 19,130 | ||
| SMC3 | bone-marrow | 15min | GEO | Mus musculus | GSE90958 | 49,555 | ||
| SMC3 | bone-marrow | ThymoDpA | GEO | Mus musculus | GSE90958 | 43,926 | ||
| SMC3 | bone-marrow | ThymoDpA-pA | GEO | Mus musculus | GSE90958 | 36,129 | ||
| SMC3 | bone-marrow | 30min | GEO | Mus musculus | GSE90958 | 44,635 | ||
| SMC3 | spleen | stimulated | GEO | Mus musculus | GSE43594 | 3,830 | ||
| SMC3 | spleen | GEO | Mus musculus | GSE43594 | 2,466 | |||
| SMC3 | MEL | ENCODE | Mus musculus | ENCSR000ETL | 31,097 | |||
| SMC3 | B-cell | activated | GEO | Mus musculus | GSE98119 | 48,350 | ||
| SMC3 | mESC | GEO | Mus musculus | GSE80049 | 65,300 | |||
| SMC3 | mESC | GEO | Mus musculus | GSE80280 | 18,379 | |||
| SMC3 | mESC | DKO | GEO | Mus musculus | GSE74055 | 5,005 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |