SMC3

Information SMC3

Description

This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]

Full Name

structural maintenance of chromosomes 3

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
29
Biotypes
16
Peaks
976,948
Non-redundant peaks
200,759

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
9126
Official Gene Name
SMC3
JASPAR
Ensembl
ENSG00000108055
UniProt
Q9UQE7
Genevisible
Q9UQE7
RefSeq
NM_005445
Aliases
BAM; BMH; CDLS3; CSPG6; HCAP; SMC3L1

External links
All peaks SMC3
Download BED file
Non redundant peaks SMC3
Download BED file
SEQUENCES SMC3
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for SMC3

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SMC3 U-937 ENA Homo sapiens ERP008568 76
SMC3 HEK293T WT GEO Homo sapiens GSE122299 19,231
SMC3 HEK293T CRISPR GEO Homo sapiens GSE122299 25,475
SMC3 GP5D GEO Homo sapiens GSE51234 60,728
SMC3 GP5D SIRAD21 GEO Homo sapiens GSE51234 13,404
SMC3 HeLa ESCO2_ESCO1_siRNA GEO Homo sapiens GSE105004 11,733
SMC3 HeLa ESCO2-deltaPBMA_ESCO1_siRNA GEO Homo sapiens GSE105004 18,488
SMC3 ac HeLa ESCO2_ctrl_siRNA GEO Homo sapiens GSE105004 836
SMC3 ac HeLa ESCO2-deltaPBMA_ctrl_siRNA GEO Homo sapiens GSE105004 236
SMC3 HeLa ESCO2-deltaPBMA_ctrl_siRNA GEO Homo sapiens GSE105004 20,088
SMC3 HeLa GEO Homo sapiens GSE126990 74,627
SMC3 SK-N-SH ENCODE Homo sapiens ENCSR000EHW 36,183
SMC3 K-562 ENCODE Homo sapiens ENCSR000EGW 36,921
SMC3 IMR-90 ENCODE Homo sapiens ENCSR000HPG 59,754
SMC3 Hep-G2 ENCODE Homo sapiens ENCSR000EDW 37,842
SMC3 A-549 ENCODE Homo sapiens ENCSR481YWD 28,281
SMC3 neural ENCODE Homo sapiens ENCSR404BPV 46,333
SMC3 GM12878 ENCODE Homo sapiens ENCSR000DZP 15,056
SMC3 CUTLL1 GEO Homo sapiens GSE130140 4,491
SMC3 hESC D0 GEO Homo sapiens GSE116862 21,602
SMC3 peripheral-blood-neutrophil GEO Homo sapiens GSE126755 19,790
SMC3 peripheral-blood-neutrophil Ecoli-1 GEO Homo sapiens GSE126755 39,389
SMC3 HeLa-S3 ENCODE Homo sapiens ENCSR000ECS 50,768
SMC3 HeLa-Kyoto PDS5-depleted GEO Homo sapiens GSE102884 67,460
SMC3 HeLa-Kyoto WAPL_PDS-depleted GEO Homo sapiens GSE102884 69,203
SMC3 HeLa-Kyoto GEO Homo sapiens GSE102884 74,609
SMC3 HeLa-Kyoto GEO Homo sapiens GSE138405 74,623
SMC3 HeLa-Kyoto ESCO1-depleted GEO Homo sapiens GSE138405 21,096
SMC3 HeLa-Kyoto WT GEO Homo sapiens GSE138405 28,625
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks