SNAI2

Information SNAI2

Description

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]

Full Name

snail family transcriptional repressor 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
16
Biotypes
5
Peaks
259,113
Non-redundant peaks
190,468

TF Classification

Super Class
Zinc-coordinating DNA-binding domains
Class
C2H2 zinc finger factors
Familly
More than 3 adjacent zinc finger factors
Sub Familly
Snail-like factors

Source TFClass

External IDs

NCBI Gene
6591
Official Gene Name
SNAI2
JASPAR
MA0745
Ensembl
ENSG00000019549
UniProt
O43623
Genevisible
O43623
RefSeq
NM_003068
Aliases
SLUG; SLUGH; SLUGH1; SNAIL2; WS2D
All peaks SNAI2
Download BED file
Non redundant peaks SNAI2
Download BED file
SEQUENCES SNAI2
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for SNAI2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SNAI2 RD shSNAI2 GEO Homo sapiens GSE137168 9,696
SNAI2 RD GEO Homo sapiens GSE137168 13,190
SNAI2 SMS-CTR GEO Homo sapiens GSE137168 1,921
SNAI2 SMS-CTR T48 GEO Homo sapiens GSE137168 47,984
SNAI2 SMS-CTR D48 GEO Homo sapiens GSE137168 44,305
SNAI2 SMS-CTR shSNAI2 GEO Homo sapiens GSE137168 29,865
SNAI2 SK-N-SH all-trans-retinoic-acid_6-uM_48-hour ENCODE Homo sapiens ENCSR106GVM 13,126
SNAI2 keratinocyte SNAI2 GEO Homo sapiens GSE55421 12,484
SNAI2 keratinocyte SHCTR GEO Homo sapiens GSE55421 7,108
SNAI2 keratinocyte LacZ GEO Homo sapiens GSE55421 25,008
SNAI2 keratinocyte SHSNAI2 GEO Homo sapiens GSE55421 879
SNAI2 keratinocyte LacZ_DIFF GEO Homo sapiens GSE55421 4,424
SNAI2 PC-9 1DF GEO Homo sapiens GSE131687 13,035
SNAI2 PC-9 2DF GEO Homo sapiens GSE131687 29,591
SNAI2 PC-9 1DF_DMSO GEO Homo sapiens GSE131687 2,337
SNAI2 PC-9 2DF_DMSO GEO Homo sapiens GSE131687 4,160
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks