SOX2
Information SOX2
- Description
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in a similar gene in human have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (Sox2ot). [provided by RefSeq, Sep 2015]
- Full Name
SRY (sex determining region Y)-box 2
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 86
- Biotypes
- 21
- Peaks
- 1,813,705
- Non-redundant peaks
- 522,120
TF Classification
- Familly
- High-mobility group (HMG) domain factors
- Sub Familly
- SOX-related factors
Source JASPAR
Datasets Table for SOX2
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
---|---|---|---|---|---|---|---|---|
SOX2 | NPC | spheres | GEO | Mus musculus | GSE90559 | 35,729 | ||
SOX2 | NPC | singles | GEO | Mus musculus | GSE90559 | 2,190 | ||
SOX2 | NPC | GEO | Mus musculus | GSE33059 | 3,625 | |||
SOX2 | NPC | GEO | Mus musculus | GSE35496 | 23,499 | |||
SOX2 | pre-iPSC | GEO | Mus musculus | GSE90893 | 62,015 | |||
SOX2 | MEF | d3_Thy1-pos | GEO | Mus musculus | GSE101905 | 47,957 | ||
SOX2 | MEF | d5_YR | GEO | Mus musculus | GSE103978 | 3,993 | ||
SOX2 | MEF | d6_Thy1-pos | GEO | Mus musculus | GSE101905 | 11,885 | ||
SOX2 | MEF | SKpMX | GEO | Mus musculus | GSE90893 | 50,711 | ||
SOX2 | MEF | d3_SSEA1-pos | GEO | Mus musculus | GSE101905 | 39,943 | ||
SOX2 | MEF | d6_SSEA1-pos | GEO | Mus musculus | GSE101905 | 34,497 | ||
SOX2 | MEF | d1_YR | GEO | Mus musculus | GSE103978 | 1,699 | ||
SOX2 | MEF | d9_SSEA1-pos | GEO | Mus musculus | GSE101905 | 29,787 | ||
SOX2 | MEF | d1 | GEO | Mus musculus | GSE102517 | 30,249 | ||
SOX2 | MEF | d3 | GEO | Mus musculus | GSE102517 | 24,349 | ||
SOX2 | MEF | d5 | GEO | Mus musculus | GSE102517 | 19,849 | ||
SOX2 | MEF | d6 | GEO | Mus musculus | GSE102517 | 6,808 | ||
SOX2 | MEF | d7 | GEO | Mus musculus | GSE102517 | 4,408 | ||
SOX2 | MEF | d4 | GEO | Mus musculus | GSE102517 | 29,959 | ||
SOX2 | MEF | shCTRL | GEO | Mus musculus | GSE99009 | 21,121 | ||
SOX2 | MEF | d5_O6 | GEO | Mus musculus | GSE103978 | 567 | ||
SOX2 | MEF | d5_O4 | GEO | Mus musculus | GSE103978 | 703 | ||
SOX2 | MEF | d1_O4 | GEO | Mus musculus | GSE103978 | 675 | ||
SOX2 | MEF | OSpMX | GEO | Mus musculus | GSE90893 | 66,461 | ||
SOX2 | MEF | SpMX | GEO | Mus musculus | GSE90893 | 44,667 | ||
SOX2 | MEF | d12_SSEA1-pos | GEO | Mus musculus | GSE101905 | 13,529 | ||
SOX2 | MEF | d8 | GEO | Mus musculus | GSE102517 | 6,096 | ||
SOX2 | MEF | d2 | GEO | Mus musculus | GSE102517 | 21,946 | ||
SOX2 | MEF | GEO | Mus musculus | GSE72744 | 29,618 | |||
SOX2 | cortex | GEO | Mus musculus | GSE85213 | 47,277 | |||
SOX2 | SCC | 20Mcells | GEO | Mus musculus | GSE104142 | 4,997 | ||
SOX2 | SCC | 1Mcells | GEO | Mus musculus | GSE104142 | 14,456 | ||
SOX2 | ZHBTc4 | GEO | Mus musculus | GSE87820 | 10,789 | |||
SOX2 | iPSC | GEO | Mus musculus | GSE102517 | 8,181 | |||
SOX2 | trophoblast-stem-cell | EGFP | GEO | Mus musculus | GSE51511 | 12,542 | ||
SOX2 | mESC | Brg1fl | GEO | Mus musculus | GSE87820 | 8,509 | ||
SOX2 | mESC | YPet-Sox2 | GEO | Mus musculus | GSE126554 | 3,035 | ||
SOX2 | mESC | KO_d2 | GEO | Mus musculus | GSE28453 | 507 | ||
SOX2 | mESC | d3 | GEO | Mus musculus | GSE28453 | 2,370 | ||
SOX2 | mESC | d1 | GEO | Mus musculus | GSE28453 | 3,739 | ||
SOX2 | mESC | d0 | GEO | Mus musculus | GSE28453 | 5,197 | ||
SOX2 | mESC | d4 | GEO | Mus musculus | GSE28453 | 2,735 | ||
SOX2 | mESC | GEO | Mus musculus | GSE44286 | 17,964 | |||
SOX2 | mESC | PARP-1KO | GEO | Mus musculus | GSE74112 | 15,872 | ||
SOX2 | mESC | rtta | GEO | Mus musculus | GSE35496 | 4,290 | ||
SOX2 | mESC | Interphase_PFA | GEO | Mus musculus | GSE122589 | 2,322 | ||
SOX2 | mESC | Halo-tag | GEO | Mus musculus | GSE54103 | 972 | ||
SOX2 | mESC | Brg1fl_Tam-72h | GEO | Mus musculus | GSE87820 | 17,205 | ||
SOX2 | mESC | d2 | GEO | Mus musculus | GSE28453 | 1,718 | ||
SOX2 | mESC | GEO | Mus musculus | GSE102517 | 12,208 | |||
SOX2 | mESC | asynchronus | GEO | Mus musculus | GSE89599 | 5,164 | ||
SOX2 | KPS | GEO | Mus musculus | GSE118244 | 67,034 | |||
SOX2 | lung | ectopic | GEO | Mus musculus | GSE108952 | 34,516 | ||
SOX2 | lung | GEO | Mus musculus | GSE108952 | 10,662 | |||
SOX2 | EBs | GEO | Mus musculus | GSE42132 | 2,214 | |||
SOX2 | AtT-20 | GEO | Mus musculus | GSE125669 | 74,249 | |||
SOX2 | NSC | ctrl | GEO | Mus musculus | GSE69859 | 59,143 | ||
SOX2 | NSC | GEO | Mus musculus | GSE134106 | 2,123 | |||
SOX2 | neuro-mesodermal-progenitors | GEO | Mus musculus | GSE93524 | 29,019 | |||
SOX2 | LSCC | GEO | Mus musculus | GSE118244 | 54,678 | |||
SOX2 | trophoblast-stem-cell | ZHBTc4 | GEO | Mus musculus | GSE51511 | 18,385 | ||
SOX2 | E14 | Q7 | GEO | Mus musculus | GSE43429 | 23,826 | ||
SOX2 | lung | ectopic_Nkx2-1-del | GEO | Mus musculus | GSE108952 | 6,528 | ||
SOX2 | EpiSC | GEO | Mus musculus | GSE103053 | 8,665 | |||
SOX2 | NSC | GEO | Mus musculus | GSE69859 | 2,347 | |||
SOX2 | fibroblast | GEO | Mus musculus | GSE119782 | 1,757 | |||
SOX2 | MEF | shUbc9 | GEO | Mus musculus | GSE99009 | 22,307 | ||
SOX2 | MEF | StetO | GEO | Mus musculus | GSE90893 | 31,086 | ||
SOX2 | MEF | IPSC_GFP-pos | GEO | Mus musculus | GSE101905 | 25,722 | ||
SOX2 | MEF | OSKpMX | GEO | Mus musculus | GSE90893 | 64,070 | ||
SOX2 | MEF | 48h | GEO | Mus musculus | GSE90893 | 66,610 | ||
SOX2 | mESC | UHRF1-KO | GEO | Mus musculus | GSE113913 | 6,129 | ||
SOX2 | mESC | Teto-POU3F2 | GEO | Mus musculus | GSE35496 | 8,379 | ||
SOX2 | mESC | Sox2KE | GEO | Mus musculus | GSE43275 | 60,711 | ||
SOX2 | mESC | Halo-tag_mutD | GEO | Mus musculus | GSE54103 | 13,762 | ||
SOX2 | mESC | GEO | Mus musculus | GSE43275 | 39,872 | |||
SOX2 | mESC | GEO | Mus musculus | GSE74112 | 17,951 | |||
SOX2 | mESC | GEO | Mus musculus | GSE74599 | 5,950 | |||
SOX2 | mESC | Dox-min | GEO | Mus musculus | GSE118898 | 22,037 | ||
SOX2 | mESC | GEO | Mus musculus | GSE59378 | 3,517 | |||
SOX2 | mESC | GEO | Mus musculus | GSE90893 | 35,171 | |||
SOX2 | mESC | Dox-plus | GEO | Mus musculus | GSE118898 | 24,209 | ||
SOX2 | mESC | GEO | Mus musculus | GSE35496 | 12,642 | |||
SOX2 | ZHBTc4 | Dox-24h | GEO | Mus musculus | GSE87820 | 52,262 | ||
SOX2 | C2C12 | GEO | Mus musculus | GSE33059 | 31,216 | |||
SOX2 | stomach | GEO | Mus musculus | GSE83965 | 4,372 | |||
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |