SOX2

Information SOX2

Description

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in a similar gene in human have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (Sox2ot). [provided by RefSeq, Sep 2015]

Full Name

SRY (sex determining region Y)-box 2

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
86
Biotypes
21
Peaks
1,813,705
Non-redundant peaks
522,120

TF Classification

Familly
High-mobility group (HMG) domain factors
Sub Familly
SOX-related factors

Source JASPAR

External IDs

NCBI Gene
20674
Official Gene Name
Sox2
JASPAR
MA0143.3
MGI
MGI:98364
Ensembl
ENSMUSG00000074637
UniProt
Genevisible
RefSeq
NM_011443
Aliases
Sox-2; lcc; ysb

External links
All peaks SOX2
Download BED file
Non redundant peaks SOX2
Download BED file
SEQUENCES SOX2
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for SOX2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SOX2 NPC spheres GEO Mus musculus GSE90559 35,729
SOX2 NPC singles GEO Mus musculus GSE90559 2,190
SOX2 NPC GEO Mus musculus GSE33059 3,625
SOX2 NPC GEO Mus musculus GSE35496 23,499
SOX2 pre-iPSC GEO Mus musculus GSE90893 62,015
SOX2 MEF d3_Thy1-pos GEO Mus musculus GSE101905 47,957
SOX2 MEF d5_YR GEO Mus musculus GSE103978 3,993
SOX2 MEF d6_Thy1-pos GEO Mus musculus GSE101905 11,885
SOX2 MEF SKpMX GEO Mus musculus GSE90893 50,711
SOX2 MEF d3_SSEA1-pos GEO Mus musculus GSE101905 39,943
SOX2 MEF d6_SSEA1-pos GEO Mus musculus GSE101905 34,497
SOX2 MEF d1_YR GEO Mus musculus GSE103978 1,699
SOX2 MEF d9_SSEA1-pos GEO Mus musculus GSE101905 29,787
SOX2 MEF d1 GEO Mus musculus GSE102517 30,249
SOX2 MEF d3 GEO Mus musculus GSE102517 24,349
SOX2 MEF d5 GEO Mus musculus GSE102517 19,849
SOX2 MEF d6 GEO Mus musculus GSE102517 6,808
SOX2 MEF d7 GEO Mus musculus GSE102517 4,408
SOX2 MEF d4 GEO Mus musculus GSE102517 29,959
SOX2 MEF shCTRL GEO Mus musculus GSE99009 21,121
SOX2 MEF d5_O6 GEO Mus musculus GSE103978 567
SOX2 MEF d5_O4 GEO Mus musculus GSE103978 703
SOX2 MEF d1_O4 GEO Mus musculus GSE103978 675
SOX2 MEF OSpMX GEO Mus musculus GSE90893 66,461
SOX2 MEF SpMX GEO Mus musculus GSE90893 44,667
SOX2 MEF d12_SSEA1-pos GEO Mus musculus GSE101905 13,529
SOX2 MEF d8 GEO Mus musculus GSE102517 6,096
SOX2 MEF d2 GEO Mus musculus GSE102517 21,946
SOX2 MEF GEO Mus musculus GSE72744 29,618
SOX2 cortex GEO Mus musculus GSE85213 47,277
SOX2 SCC 20Mcells GEO Mus musculus GSE104142 4,997
SOX2 SCC 1Mcells GEO Mus musculus GSE104142 14,456
SOX2 ZHBTc4 GEO Mus musculus GSE87820 10,789
SOX2 iPSC GEO Mus musculus GSE102517 8,181
SOX2 trophoblast-stem-cell EGFP GEO Mus musculus GSE51511 12,542
SOX2 mESC Brg1fl GEO Mus musculus GSE87820 8,509
SOX2 mESC YPet-Sox2 GEO Mus musculus GSE126554 3,035
SOX2 mESC KO_d2 GEO Mus musculus GSE28453 507
SOX2 mESC d3 GEO Mus musculus GSE28453 2,370
SOX2 mESC d1 GEO Mus musculus GSE28453 3,739
SOX2 mESC d0 GEO Mus musculus GSE28453 5,197
SOX2 mESC d4 GEO Mus musculus GSE28453 2,735
SOX2 mESC GEO Mus musculus GSE44286 17,964
SOX2 mESC PARP-1KO GEO Mus musculus GSE74112 15,872
SOX2 mESC rtta GEO Mus musculus GSE35496 4,290
SOX2 mESC Interphase_PFA GEO Mus musculus GSE122589 2,322
SOX2 mESC Halo-tag GEO Mus musculus GSE54103 972
SOX2 mESC Brg1fl_Tam-72h GEO Mus musculus GSE87820 17,205
SOX2 mESC d2 GEO Mus musculus GSE28453 1,718
SOX2 mESC GEO Mus musculus GSE102517 12,208
SOX2 mESC asynchronus GEO Mus musculus GSE89599 5,164
SOX2 KPS GEO Mus musculus GSE118244 67,034
SOX2 lung ectopic GEO Mus musculus GSE108952 34,516
SOX2 lung GEO Mus musculus GSE108952 10,662
SOX2 EBs GEO Mus musculus GSE42132 2,214
SOX2 AtT-20 GEO Mus musculus GSE125669 74,249
SOX2 NSC ctrl GEO Mus musculus GSE69859 59,143
SOX2 NSC GEO Mus musculus GSE134106 2,123
SOX2 neuro-mesodermal-progenitors GEO Mus musculus GSE93524 29,019
SOX2 LSCC GEO Mus musculus GSE118244 54,678
SOX2 trophoblast-stem-cell ZHBTc4 GEO Mus musculus GSE51511 18,385
SOX2 E14 Q7 GEO Mus musculus GSE43429 23,826
SOX2 lung ectopic_Nkx2-1-del GEO Mus musculus GSE108952 6,528
SOX2 EpiSC GEO Mus musculus GSE103053 8,665
SOX2 NSC GEO Mus musculus GSE69859 2,347
SOX2 fibroblast GEO Mus musculus GSE119782 1,757
SOX2 MEF shUbc9 GEO Mus musculus GSE99009 22,307
SOX2 MEF StetO GEO Mus musculus GSE90893 31,086
SOX2 MEF IPSC_GFP-pos GEO Mus musculus GSE101905 25,722
SOX2 MEF OSKpMX GEO Mus musculus GSE90893 64,070
SOX2 MEF 48h GEO Mus musculus GSE90893 66,610
SOX2 mESC UHRF1-KO GEO Mus musculus GSE113913 6,129
SOX2 mESC Teto-POU3F2 GEO Mus musculus GSE35496 8,379
SOX2 mESC Sox2KE GEO Mus musculus GSE43275 60,711
SOX2 mESC Halo-tag_mutD GEO Mus musculus GSE54103 13,762
SOX2 mESC GEO Mus musculus GSE43275 39,872
SOX2 mESC GEO Mus musculus GSE74112 17,951
SOX2 mESC GEO Mus musculus GSE74599 5,950
SOX2 mESC Dox-min GEO Mus musculus GSE118898 22,037
SOX2 mESC GEO Mus musculus GSE59378 3,517
SOX2 mESC GEO Mus musculus GSE90893 35,171
SOX2 mESC Dox-plus GEO Mus musculus GSE118898 24,209
SOX2 mESC GEO Mus musculus GSE35496 12,642
SOX2 ZHBTc4 Dox-24h GEO Mus musculus GSE87820 52,262
SOX2 C2C12 GEO Mus musculus GSE33059 31,216
SOX2 stomach GEO Mus musculus GSE83965 4,372
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks