SOX8
Information SOX8
- Description
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the cognitive disability found in an alpha-thalassemia-related syndrome (ART-16). This protein is also highly expressed in the majority of human hepatocellular carcinomas and promotes cellular proliferation and enhanced tumor growth. [provided by RefSeq, Jul 2017]
- Full Name
SRY-box transcription factor 8
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 3
- Biotypes
- 1
- Peaks
- 95,610
- Non-redundant peaks
- 82,079
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
Datasets Table for SOX8
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SOX8 | RH4 | GEO | Homo sapiens | GSE116344 | 41,234 | |||
| SOX8 | RH4 | Entinostat-6H | GEO | Homo sapiens | GSE116344 | 35,116 | ||
| SOX8 | RH4 | DMSO-6H | GEO | Homo sapiens | GSE116344 | 19,260 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |