SP3
Information SP3
- Description
This gene product belongs to a family of Sp1 related transcription factors, which regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses transcription of numerous genes. Alternative splicing results in transcript variants encoding different isoforms, and one variant initiates translation from a non-AUG (AUA) codon. [provided by RefSeq, Jul 2008]
- Full Name
trans-acting transcription factor 3
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 8
- Biotypes
- 2
- Peaks
- 292,756
- Non-redundant peaks
- 96,117
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 20687
- Official Gene Name
- Sp3
- JASPAR
- MGI
- MGI:1277166
- Ensembl
- ENSMUSG00000027109
- UniProt
- O70494
- Genevisible
- O70494
- RefSeq
- NM_001098425
- Aliases
- D130027J01Rik
Datasets Table for SP3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SP3 | Flk1 | DNA-Binding | GEO | Mus musculus | GSE126496 | 29,361 | ||
| SP3 | Flk1 | GEO | Mus musculus | GSE126496 | 31,819 | |||
| SP3 | mESC | Sp1-KO | GEO | Mus musculus | GSE126496 | 48,320 | ||
| SP3 | mESC | Sp1-het | GEO | Mus musculus | GSE126496 | 58,555 | ||
| SP3 | mESC | GEO | Mus musculus | GSE126496 | 42,490 | |||
| SP3 | Flk1 | Sp1-het | GEO | Mus musculus | GSE126496 | 43,598 | ||
| SP3 | mESC | DNA-Binding | GEO | Mus musculus | GSE126496 | 33,241 | ||
| SP3 | mESC | GEO | Mus musculus | GSE116704 | 5,372 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |