SPI1

Information SPI1

Description

Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. {ECO:0000269|PubMed:8626664}.(Source UnitProtKB).

Full Name

spleen focus forming virus (SFFV) proviral integration oncogene

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
121
Biotypes
32
Peaks
5,364,369
Non-redundant peaks
593,602

TF Classification

Familly
Tryptophan cluster factors
Sub Familly
Ets-related factors

Source JASPAR

External IDs

NCBI Gene
20375
Official Gene Name
Spi1
JASPAR
MA0080.3
MGI
MGI:98282
Ensembl
ENSMUSG00000002111
UniProt
P17433
Genevisible
P17433
RefSeq
NM_011355
Aliases
Dis-1; Dis1; PU.1; Sfpi-1; Sfpi1; Spi-1; Tcfpu1; Tfpu.1

External links
All peaks SPI1
Download BED file
Non redundant peaks SPI1
Download BED file
SEQUENCES SPI1
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for SPI1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SPI1 spleen GEO Mus musculus GSE134583 33,441
SPI1 spleen Stag2-KO GEO Mus musculus GSE134583 27,262
SPI1 spleen GEO Mus musculus GSE99165 450
SPI1 erythroleukemia D5 GEO Mus musculus GSE67955 6,248
SPI1 erythroleukemia D0 GEO Mus musculus GSE67955 24,915
SPI1 T-cell OHT-0h GEO Mus musculus GSE93755 29,169
SPI1 T-cell ENGHA GEO Mus musculus GSE93755 75,190
SPI1 T-cell OHT-24h GEO Mus musculus GSE93755 2,820
SPI1 T-cell OHT-0h_ert2 GEO Mus musculus GSE93755 27,198
SPI1 multipotent-progenitor GEO Mus musculus GSE57563 8,174
SPI1 neutrophil GEO Mus musculus GSE110863 71,366
SPI1 HPC-7 GEO Mus musculus GSE22178 32,821
SPI1 pre-B-cell 48h GEO Mus musculus GSE53362 50,185
SPI1 pre-B-cell 12h GEO Mus musculus GSE53362 76,150
SPI1 pre-B-cell 3h GEO Mus musculus GSE53362 43,129
SPI1 pre-B-cell 24h GEO Mus musculus GSE53362 49,042
SPI1 pDC GEO Mus musculus GSE121544 45,706
SPI1 BMDC 2h GEO Mus musculus GSE36099 70,364
SPI1 BMDC 30min GEO Mus musculus GSE36099 75,629
SPI1 BMDC 1h GEO Mus musculus GSE36099 74,746
SPI1 macrophage hybrid GEO Mus musculus GSE46494 56,522
SPI1 macrophage LPM_DMSO GEO Mus musculus GSE62826 11,858
SPI1 macrophage MAF-DKO GEO Mus musculus GSE75722 78,378
SPI1 macrophage GEO Mus musculus GSE48759 14,974
SPI1 macrophage Kdo2-LipidA GEO Mus musculus GSE46494 71,229
SPI1 macrophage LPM GEO Mus musculus GSE62826 13,732
SPI1 macrophage KLA-1h GEO Mus musculus GSE111854 67,426
SPI1 macrophage NR1D1-bio GEO Mus musculus GSE45914 33,696
SPI1 macrophage GEO Mus musculus GSE45914 17,447
SPI1 macrophage LPM_NOD GEO Mus musculus GSE62826 36,104
SPI1 macrophage LPM_VehTGFB1 GEO Mus musculus GSE62826 53,975
SPI1 macrophage IBET-2h GEO Mus musculus GSE48759 25,682
SPI1 macrophage B6_Kdo2-LipidA GEO Mus musculus GSE46494 70,386
SPI1 macrophage Flavo-7h GEO Mus musculus GSE48759 43,834
SPI1 macrophage LPM_ATRA GEO Mus musculus GSE62826 62,508
SPI1 macrophage veh GEO Mus musculus GSE111854 51,956
SPI1 macrophage LPM_SPRET GEO Mus musculus GSE62826 25,957
SPI1 macrophage KLA-1h GEO Mus musculus GSE48759 55,115
SPI1 WEHI-279 GEO Mus musculus GSE58128 5,933
SPI1 plasmablast GEO Mus musculus GSE71698 66,422
SPI1 fetal-liver DN1 GEO Mus musculus GSE31233 38,945
SPI1 fetal-liver DN2b GEO Mus musculus GSE31233 9,991
SPI1 fetal-liver DN2a GEO Mus musculus GSE31233 56,554
SPI1 dendritic-cell-progenitor common GEO Mus musculus GSE57563 23,147
SPI1 hematopoietic-progenitor LSD1i_IRF8-sc GEO Mus musculus GSE110896 30,147
SPI1 hematopoietic-progenitor IBET_IRF8-sc GEO Mus musculus GSE110896 58,800
SPI1 hematopoietic-progenitor DMSO GEO Mus musculus GSE110896 41,466
SPI1 hematopoietic-progenitor LSD1i GEO Mus musculus GSE110896 40,766
SPI1 AML GEO Mus musculus GSE79191 34,873
SPI1 AML EV GEO Mus musculus GSE63317 7,810
SPI1 AML restoration-D0 GEO Mus musculus GSE108945 5,675
SPI1 AML restoration-D8 GEO Mus musculus GSE108945 37,882
SPI1 AML restoration-D4 GEO Mus musculus GSE108945 77,563
SPI1 AML restoration-D12 GEO Mus musculus GSE108945 75,807
SPI1 AML KO-D4 GEO Mus musculus GSE108945 18,197
SPI1 AML KO-D0 GEO Mus musculus GSE108945 11,713
SPI1 FDCP-Mix N GEO Mus musculus GSE50406 35,526
SPI1 FDCP-Mix E GEO Mus musculus GSE50406 4,837
SPI1 FDCP-Mix MP GEO Mus musculus GSE50406 25,293
SPI1 dendritic-cell GEO Mus musculus GSE121544 63,908
SPI1 dendritic-cell plasmacytoid GEO Mus musculus GSE57563 20,198
SPI1 dendritic-cell classical GEO Mus musculus GSE57563 34,805
SPI1 CD25-pos GEO Mus musculus GSE93755 20,030
SPI1 pro-B-cell GEO Mus musculus GSE53595 41,267
SPI1 pro-B-cell GEO Mus musculus GSE87314 65,116
SPI1 CD8-pos CpG GEO Mus musculus GSE106730 62,699
SPI1 bone-marrow RANKL-72h GEO Mus musculus GSE107294 10,031
SPI1 bone-marrow GEO Mus musculus GSE134583 54,460
SPI1 bone-marrow Ly6Clo GEO Mus musculus GSE80031 59,301
SPI1 bone-marrow LPS GEO Mus musculus GSE123347 68,928
SPI1 bone-marrow GEO Mus musculus GSE107294 44,676
SPI1 bone-marrow Ly6Chi GEO Mus musculus GSE80031 65,707
SPI1 bone-marrow Stag2-KO GEO Mus musculus GSE134583 42,473
SPI1 bone-marrow moDC GEO Mus musculus GSE62702 75,493
SPI1 AML-246 GEO Mus musculus GSE76933 42,624
SPI1 BV-2 Nwt GEO Mus musculus GSE54443 43,021
SPI1 BV-2 pCDH GEO Mus musculus GSE54443 71,831
SPI1 lymph-node GEO Mus musculus GSE128166 22,637
SPI1 BMDM IL4-1h GEO Mus musculus GSE107456 52,231
SPI1 BMDM GEO Mus musculus GSE50762 47,286
SPI1 BMDM homog-6h GEO Mus musculus GSE72964 31,558
SPI1 BMDM GEO Mus musculus GSE106701 73,401
SPI1 BMDM shSpi1 GEO Mus musculus GSE50762 34,464
SPI1 BMDM IV_Spi1-depleted GEO Mus musculus GSE50762 407
SPI1 BMDM KLA_SPRET GEO Mus musculus GSE109965 70,594
SPI1 BMDM GEO Mus musculus GSE75722 74,420
SPI1 BMDM veh-6h GEO Mus musculus GSE72964 55,466
SPI1 BMDM GEO Mus musculus GSE107456 41,943
SPI1 BMDM IFNg_30min GEO Mus musculus GSE38377 77,188
SPI1 BMDM IL4-6h GEO Mus musculus GSE107456 65,886
SPI1 BMDM STAT1-KO_ctrl GEO Mus musculus GSE38377 77,781
SPI1 myeloid-progenitor GEO Mus musculus GSE69776 6,139
SPI1 primary-macrophage GEO Mus musculus GSE21314 50,896
SPI1 microglia NOD GEO Mus musculus GSE62826 16,745
SPI1 microglia SPRET GEO Mus musculus GSE62826 17,627
SPI1 microglia GEO Mus musculus GSE62826 53,221
SPI1 neutrophil Ca-stimulated GEO Mus musculus GSE110863 50,941
SPI1 primary-B-cell d1 GEO Mus musculus GSE46607 21,195
SPI1 primary-B-cell d3 GEO Mus musculus GSE46607 23,896
SPI1 bone-marrow RANKL-36h GEO Mus musculus GSE107294 41,255
SPI1 bone-marrow vitc GEO Mus musculus GSE87623 27,317
SPI1 bone-marrow pDC GEO Mus musculus GSE62702 76,599
SPI1 bone-marrow gmpM GEO Mus musculus GSE89767 14,314
SPI1 bone-marrow gmpG GEO Mus musculus GSE89767 21,709
SPI1 pre-B-cell 0h GEO Mus musculus GSE53362 37,739
SPI1 BMDM IL4-24h GEO Mus musculus GSE107456 75,348
SPI1 BMDM IFNg GEO Mus musculus GSE38377 79,228
SPI1 BMDM IV_Igg-depleted GEO Mus musculus GSE50762 41,036
SPI1 BMDM IFNg_2h GEO Mus musculus GSE38377 78,835
SPI1 macrophage LPM_TGFB1 GEO Mus musculus GSE62826 46,912
SPI1 macrophage DMSO-2h GEO Mus musculus GSE48759 70,084
SPI1 hematopoietic-progenitor IBET GEO Mus musculus GSE110896 22,183
SPI1 liver Gran2D GEO Mus musculus GSE42110 59,022
SPI1 pro-B-cell GEO Mus musculus GSE21614 8,808
SPI1 CD8-pos plC GEO Mus musculus GSE106730 66,141
SPI1 CD8-pos GEO Mus musculus GSE106730 70,826
SPI1 BMDC GEO Mus musculus GSE36099 79,124
SPI1 AML PuER GEO Mus musculus GSE63317 24,610
SPI1 AML Dox GEO Mus musculus GSE79191 72,018
SPI1 3T3-L1 Spi1-Ad GEO Mus musculus GSE48343 71,320
SPI1 BV-2 Nmu GEO Mus musculus GSE54443 71,003
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks