SRC

Information SRC

Description

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Full Name

SRC proto-oncogene, non-receptor tyrosine kinase

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
4
Biotypes
1
Peaks
9,129
Non-redundant peaks
5,927

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
6714
Official Gene Name
SRC
JASPAR
Ensembl
ENSG00000197122
UniProt
P12931
Genevisible
P12931
RefSeq
NM_005417
Aliases
ASV; SRC1; THC6; c-SRC; c-src; p60-Src
All peaks SRC
Download BED file
Non redundant peaks SRC
Download BED file
SEQUENCES SRC
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for SRC

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SRC MDA-MB-231 LQ_45min GEO Homo sapiens GSE95121 3,579
SRC MDA-MB-231 45min GEO Homo sapiens GSE95121 2,493
SRC MDA-MB-231 LQ GEO Homo sapiens GSE95121 2,769
SRC MDA-MB-231 GEO Homo sapiens GSE95121 288
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks