SREBP2

Information SREBP2

Description

This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Full Name

sterol regulatory element binding transcription factor 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
8
Biotypes
6
Peaks
194,967
Non-redundant peaks
127,102

TF Classification

Super Class
Basic domains
Class
Basic helix-loop-helix factors (bHLH)
Familly
bHLH-ZIP factors
Sub Familly
SREBP factors

Source TFClass

External IDs

NCBI Gene
6721
Official Gene Name
SREBF2
JASPAR
MA0828
Ensembl
ENSG00000198911
UniProt
Q12772
Genevisible
Q12772
RefSeq
NM_004599
Aliases
SREBP-2; SREBP2; bHLHd2
All peaks SREBP2
Download BED file
Non redundant peaks SREBP2
Download BED file
SEQUENCES SREBP2
Download FASTA file
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Datasets Table for SREBP2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SREBF2 Hep-G2 ENCODE Homo sapiens ENCSR000EZO 275
SREBF2 A-549 ENCODE Homo sapiens ENCSR638QYO 411
SREBF2 GM12878 ENCODE Homo sapiens ENCSR000DYT 655
SREBF2 monocyte TNF GEO Homo sapiens GSE129202 61,222
SREBF2 monocyte GEO Homo sapiens GSE129202 44,464
SREBF2 HCC70 GEO Homo sapiens GSE126380 55,525
SREBF2 HCC70 XY018 GEO Homo sapiens GSE126380 33,756
SREBF2 HeLa-S3 ENCODE Homo sapiens ENCSR611WZO 22,785
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks