SREBP2
Information SREBP2
- Description
This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Full Name
sterol regulatory element binding transcription factor 2
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 8
- Biotypes
- 6
- Peaks
- 194,967
- Non-redundant peaks
- 127,102
TF Classification
- Super Class
- Basic domains
- Class
- Basic helix-loop-helix factors (bHLH)
- Familly
- bHLH-ZIP factors
- Sub Familly
- SREBP factors
Source TFClass
Datasets Table for SREBP2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SREBF2 | Hep-G2 | ENCODE | Homo sapiens | ENCSR000EZO | 275 | |||
| SREBF2 | A-549 | ENCODE | Homo sapiens | ENCSR638QYO | 411 | |||
| SREBF2 | GM12878 | ENCODE | Homo sapiens | ENCSR000DYT | 655 | |||
| SREBF2 | monocyte | TNF | GEO | Homo sapiens | GSE129202 | 61,222 | ||
| SREBF2 | monocyte | GEO | Homo sapiens | GSE129202 | 44,464 | |||
| SREBF2 | HCC70 | GEO | Homo sapiens | GSE126380 | 55,525 | |||
| SREBF2 | HCC70 | XY018 | GEO | Homo sapiens | GSE126380 | 33,756 | ||
| SREBF2 | HeLa-S3 | ENCODE | Homo sapiens | ENCSR611WZO | 22,785 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |